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MGP004532

UniProt Annotations

Entry Information
Gene Nameactin binding LIM protein family, member 3
Protein EntryABLM3_HUMAN
UniProt IDO94929
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=4; Name=1; IsoId=O94929-1; Sequence=Displayed; Name=2; IsoId=O94929-2; Sequence=VSP_012127, VSP_012128, VSP_012130; Note=No experimental confirmation available.; Name=3; IsoId=O94929-3; Sequence=VSP_012127, VSP_012129; Note=No experimental confirmation available.; Name=4; IsoId=O94929-4; Sequence=VSP_012126; Note=No experimental confirmation available.;
FunctionMay act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity. {ECO:0000269|PubMed:17194709}.
Sequence CautionSequence=BAA74866.2; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityContains 1 HP (headpiece) domain. {ECO:0000255|PROSITE-ProRule:PRU00595}.
SimilarityContains 4 LIM zinc-binding domains. {ECO:0000255|PROSITE-ProRule:PRU00125}.
Subcellular LocationCytoplasm {ECO:0000250}.
SubunitDirectly interacts with F-actin and ABRA. {ECO:0000269|PubMed:17194709}.
Tissue SpecificityExpressed predominantly in heart and brain. {ECO:0000269|PubMed:17194709}.
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