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MGP004600

Record overview

MGPD IDMGP004600
Gene ID23169
SpeciesHomo sapiens (Human)
Gene Namesolute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
Gene Symbol SLC35D1
SynonymsUGTREL7;
Alternate namesUDP-glucuronic acid/UDP-N-acetylgalactosamine transporter; UDP-GlcA/UDP-GalNAc transporter; UDP-galactose transporter-related 7; UDP-galactose transporter-related protein 7; solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1; solute carrier family 35 member D1;
Chromosome1
Map Location1p32-p31
SummaryGlycosylation of cellular glycoconjugates occurs in the endoplasmic reticulum (ER) and Golgi compartment, and requires transport of nucleotide sugars from the cytosol into the lumen of the ER and Golgi by specific transporters. The protein encoded by this gene resides in the ER, and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen. It may participate in glucuronidation and/or chondroitin sulfate biosynthesis. Mutations in this gene are associated with Schneckenbecken dysplasia.[provided by RefSeq, Sep 2009]
OrthologsView orthologs and multiple alignments for SLC35D1

Proteins

UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter
Refseq ID:NP_055954
Protein GI:14028875
UniProt ID:Q9NTN3
mRNA ID:NM_015139
Length:355
RefSeq Status:
MAEVHRRQHARVKGEAPAKSSTLRDEEELGMASAETLTVFLKLLAAGFYGVSSFLIVVVNKSVLTNYRFPSSLCVGLGQMVATVAVLWVGKALRVVKFPD
LDRNVPRKTFPLPLLYFGNQITGLFSTKKLNLPMFTVLRRFSILFTMFAEGVLLKKTFSWGIKMTVFAMIIGAFVAASSDLAFDLEGYAFILINDVLTAA
NGAYVKQKLDSKELGKYGLLYYNALFMILPTLAIAYFTGDAQKAVEFEGWADTLFLLQFTLSCVMGFILMYATVLCTQYNSALTTTIVGCIKNILITYIG
MVFGGDYIFTWTNFIGLNISIAGSLVYSYITFTEEQLSKQSEANNKLDIKGKGAV
 
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