MGP Database

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MGP004991

Record overview

MGPD IDMGP004991
Gene ID29088
SpeciesHomo sapiens (Human)
Gene Namemitochondrial ribosomal protein L15
Gene Symbol MRPL15
SynonymsL15mt; RPML7; MRP-L7; HSPC145; MRP-L15;
Alternate names39S ribosomal protein L15, mitochondrial;
Chromosome8
Map Location8q11.2-q13
SummaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for MRPL15

Proteins

39S ribosomal protein L15, mitochondrial
Refseq ID:NP_054894
Protein GI:7661806
UniProt ID:Q9P015
mRNA ID:NM_014175
Length:296
RefSeq Status:
MAGPLQGGGARALDLLRGLPRVSLANLKPNPGSKKPERRPRGRRRGRKCGRGHKGERQRGTRPRLGFEGGQTPFYIRIPKYGFNEGHSFRRQYKPLSLNR
LQYLIDLGRVDPSQPIDLTQLVNGRGVTIQPLKRDYGVQLVEEGADTFTAKVNIEVQLASELAIAAIEKNGGVVTTAFYDPRSLDIVCKPVPFFLRGQPI
PKRMLPPEELVPYYTDAKNRGYLADPAKFPEARLELARKYGYILPDITKDELFKMLCTRKDPRQIFFGLAPGWVVNMADKKILKPTDENLLKYYTS
 
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