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MGP005362

UniProt Annotations

Entry Information
Gene Namepentatricopeptide repeat domain 3
Protein EntryPTCD3_HUMAN
UniProt IDQ96EY7
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q96EY7-1; Sequence=Displayed; Name=2; IsoId=Q96EY7-2; Sequence=VSP_028191, VSP_028192; Note=No experimental confirmation available.;
FunctionMitochondrial RNA-binding protein that has a role in mitochondrial translation. {ECO:0000269|PubMed:19427859}.
SimilarityBelongs to the PTCD3 family. {ECO:0000305}.
SimilarityContains 10 PPR (pentatricopeptide) repeats. {ECO:0000255|PROSITE-ProRule:PRU00708}.
Subcellular LocationMitochondrion {ECO:0000269|PubMed:19427859, ECO:0000269|PubMed:23908630}.
SubunitComponent of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins. Associated with the 12S mitochondrial rRNA (12S mt-rRNA). {ECO:0000269|PubMed:19427859, ECO:0000269|PubMed:23908630}.
Tissue SpecificityAbundant in testes, skeletal muscle and heart tissue. {ECO:0000269|PubMed:19427859}.
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