MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP005510

UniProt Annotations

Entry Information
Gene Namesolute carrier family 22 (organic anion/urate transporter), member 11
Protein EntryS22AB_HUMAN
UniProt IDQ9NSA0
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9NSA0-1; Sequence=Displayed; Name=2; IsoId=Q9NSA0-2; Sequence=VSP_018319; Note=No experimental confirmation available.;
FunctionMediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds. {ECO:0000269|PubMed:10660625, ECO:0000269|PubMed:15102942, ECO:0000269|PubMed:15291761}.
PtmN-glycosylated. Contains several complex-type N-glycans. {ECO:0000269|PubMed:15576633}.
Sequence CautionSequence=BAC11483.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. {ECO:0000305}.
Subcellular LocationCell membrane {ECO:0000269|PubMed:15291761, ECO:0000269|PubMed:15576633}; Multi-pass membrane protein {ECO:0000269|PubMed:15291761, ECO:0000269|PubMed:15576633}.
Tissue SpecificityDetected in placenta and kidney. {ECO:0000269|PubMed:10660625}.
  logo