MGP Database

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MGP005920

Ontology/Pathway Information

Entrez Gene ID79813
Gene Nameeuchromatic histone-lysine N-methyltransferase 1
Gene Symbol EHMT1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005694 IEA:UniProtKB-SubCellCchromosome
GO:0005737 IDA:HPACcytoplasm
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 ISS:UniProtKBCnucleus
GO:0005886 IDA:HPACplasma membrane
GO:0018024 IDA:UniProtKBFhistone-lysine N-methyltransferase activity
GO:0046976 ISS:UniProtKBFhistone methyltransferase activity (H3-K27 specific)
GO:0046974 ISS:UniProtKBFhistone methyltransferase activity (H3-K9 specific)
GO:0008168 IDA:UniProtKBFmethyltransferase activity
GO:0002039 IPI:UniProtKBFp53 binding
GO:0016279 IDA:UniProtKBFprotein-lysine N-methyltransferase activity
GO:0008270 IEA:InterProFzinc ion binding
GO:0016568 IDA:UniProtKBPchromatin modification
GO:0006306 ISS:UniProtKBPDNA methylation
GO:0009790 ISS:UniProtKBPembryo development
GO:0016571 IDA:UniProtKBPhistone methylation
GO:0045892 ISS:UniProtKBPnegative regulation of transcription, DNA-templated
GO:0000122 IEA:EnsemblPnegative regulation of transcription from RNA polymerase II promoter
GO:0018027 IDA:UniProtKBPpeptidyl-lysine dimethylation
GO:0018026 ISS:UniProtKBPpeptidyl-lysine monomethylation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_120956Cellular responses to stress
REACT_169274Cellular Senescence
REACT_264165Chromatin modifying enzymes
REACT_264155Chromatin organization
REACT_268728PKMTs methylate histone lysines
REACT_169168Senescence-Associated Secretory Phenotype (SASP)
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