MGP Database

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MGP006056

Ontology/Pathway Information

Entrez Gene ID81792
Gene NameADAM metallopeptidase with thrombospondin type 1 motif, 12
Gene Symbol ADAMTS12
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031012 IDA:BHF-UCLCextracellular matrix
GO:0005578 IEA:UniProtKB-SubCellCproteinaceous extracellular matrix
GO:0004222 IDA:BHF-UCLFmetalloendopeptidase activity
GO:0008270 IEA:InterProFzinc ion binding
GO:0007160 IMP:BHF-UCLPcell-matrix adhesion
GO:0016477 IMP:BHF-UCLPcell migration
GO:0071773 IDA:BHF-UCLPcellular response to BMP stimulus
GO:0071347 IMP:BHF-UCLPcellular response to interleukin-1
GO:0071356 IMP:BHF-UCLPcellular response to tumor necrosis factor
GO:2001113 IDA:BHF-UCLPnegative regulation of cellular response to hepatocyte growth factor stimulus
GO:1902548 IDA:BHF-UCLPnegative regulation of cellular response to vascular endothelial growth factor stimulus
GO:0032331 IDA:BHF-UCLPnegative regulation of chondrocyte differentiation
GO:1902203 IDA:BHF-UCLPnegative regulation of hepatocyte growth factor receptor signaling pathway
GO:0030167 IDA:BHF-UCLPproteoglycan catabolic process
GO:0051603 IDA:BHF-UCLPproteolysis involved in cellular protein catabolic process
GO:1901509 IDA:BHF-UCLPregulation of endothelial tube morphogenesis
GO:0050727 IDA:BHF-UCLPregulation of inflammatory response
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_17015Metabolism of proteins
REACT_264269O-glycosylation of TSR domain-containing proteins
REACT_263902O-linked glycosylation
REACT_22161Post-translational protein modification
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