MGP Database

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MGP006116

UniProt Annotations

Entry Information
Gene Namefatty acyl CoA reductase 1
Protein EntryFACR1_HUMAN
UniProt IDQ8WVX9
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityHexadecanal + CoA + NADP(+) = hexadecanoyl-CoA + NADPH. {ECO:0000269|PubMed:15220348}.
FunctionCatalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols. {ECO:0000269|PubMed:15220348}.
InteractionQ9BUV8:C20orf24; NbExp=1; IntAct=EBI-1045879, EBI-1050079;
SimilarityBelongs to the fatty acyl-CoA reductase family. {ECO:0000305}.
Subcellular LocationPeroxisome membrane {ECO:0000269|PubMed:24108123}; Single-pass membrane protein {ECO:0000269|PubMed:24108123}.
SubunitInteracts (via C-terminus) with PEX19, the interaction is required for targeting to peroxisomes. {ECO:0000269|PubMed:24108123}.
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