MGP Database

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MGP006229

UniProt Annotations

Entry Information
Gene Nameheparan sulfate 6-O-sulfotransferase 2
Protein EntryH6ST2_HUMAN
UniProt IDQ96MM7
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q96MM7-1; Sequence=Displayed; Name=2; Synonyms=HS6ST-2S; IsoId=Q96MM7-2; Sequence=VSP_015846; Name=3; Synonyms=HS6ST-2; IsoId=Q96MM7-3; Sequence=VSP_015846, VSP_015847; Note=No experimental confirmation available.; Name=4; IsoId=Q96MM7-4; Sequence=VSP_015847; Note=Gene prediction based on EST data.;
Catalytic Activity3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 6-sulfate.
Function6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
SimilarityBelongs to the sulfotransferase 6 family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
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