MGP Database

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MGP006371

Record overview

MGPD IDMGP006371
Gene ID116541
SpeciesHomo sapiens (Human)
Gene Namemitochondrial ribosomal protein L54
Gene Symbol MRPL54
SynonymsL54mt; MRP-L54;
Alternate names39S ribosomal protein L54, mitochondrial;
Chromosome19
Map Location19p13.3
SummaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for MRPL54

Proteins

39S ribosomal protein L54, mitochondrial
Refseq ID:NP_758455
Protein GI:27436908
UniProt ID:Q6P161
mRNA ID:NM_172251
Length:138
RefSeq Status:
MATKRLFGATRTWAGWGAWELLNPATSGRLLARDYAKKPVMKGAKSGKGAVTSEALKDPDVCTDPVQLTTYAMGVNIYKEGQDVPLKPDAEYPEWLFEMN
LGPPKTLEELDPESREYWRRLRKQNIWRHNRLSKNKRL
 
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