MGP Database

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MGP006500

UniProt Annotations

Entry Information
Gene Namephosphatidylinositol glycan anchor biosynthesis, class U
Protein EntryPIGU_HUMAN
UniProt IDQ9H490
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9H490-1; Sequence=Displayed; Name=2; IsoId=Q9H490-2; Sequence=VSP_009543; Note=No experimental confirmation available.;
FunctionComponent of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI. {ECO:0000269|PubMed:12802054}.
PathwayGlycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
SimilarityBelongs to the PIGU family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
SubunitForms a complex with PIGK/GPI8, PIGS, PIGT and GPAA1/GAA1. {ECO:0000269|PubMed:12802054}.
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