MGP Database

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MGP007263

UniProt Annotations

Entry Information
Gene Nameglucoside xylosyltransferase 2
Protein EntryGXLT2_HUMAN
UniProt IDA0PJZ3
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityUDP-alpha-D-xylose + beta-D-glucosyl-R = UDP + alpha-D-xylose-(1->3)-beta-D-glucosyl-R.
FunctionGlycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose. {ECO:0000269|PubMed:19940119}.
Sequence CautionSequence=AAI27734.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
SimilarityBelongs to the glycosyltransferase 8 family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
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