• Invitation to Nominate Compounds for Synthesis

    As part of the NIH Common Fund's Metabolomics Program, the Metabolite Standards Synthesis Core (MSSC) aims to provide metabolomics researchers with high quality metabolite standards.

    We invite scientists to nominate compounds for synthesis. Nominated compounds will be reviewed by the NIH Common Fund’s executive committee, and prioritized for synthesis.

  • Metabolomics Workbench Highlights

    Identification of Altered Metabolic Pathways in Plasma and CSF in Mild Cognitive Impairment and Alzheimer’s Disease Using Metabolomics

    In this project from the Mayo clinic, researchers examined global metabolic changes in both plasma and cerebrospinal fluid (CSF) from individuals representing the spectrum of Alzheimer’s Disease - ranging from cognitively normal (CN) to mild cognitive impairment (MCI) to Alzheimer’s Disease (AD). Data produced from their non-targeted metabolomics approach, point to alterations in a number of metabolic pathways, and pave the way for identification of novel therapeutic targets.

    Reference: Identification of altered metabolic pathways in plasma and CSF in mild cognitive impairment and Alzheimer's disease using metabolomics. PLoS One. 2013 May 20;8(5):e63644.
    doi: 10.1371/journal.pone.0063644

  • Research Library

    Network motifs provide signatures that characterize metabolism
    Shellman ER, Burant CF, Schnell S
    Mol Biosyst. 2013 Mar;9(3):352-60
    PMID: 23287894

    Isotopic ratio outlier analysis global metabolomics of Caenorhabditis elegans.
    Stupp GS, Clendinen CS, Ajredini R, Szewc MA, Garrett T, Menger RF, Yost RA, Beecher C, Edison AS
    Anal Chem. 2013 Dec 17;85(24):11858-65. doi: 10.1021/ac4025413. Epub 2013 Dec 4.
    PMID: 24274725

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Regional Comprehensive Metabolomics Resource Cores (RCMRC)s
Michigan Regional Comprehensive Metabolomics Resource Core (MRC)2
NIH West Coast Metabolomics Center at UC Davis
NIH Eastern Regional Comprehensive Metabolomics Resource Core at RTI International
Southeast Center for Integrated Metabolomics (SECIM)
Resource Center for Stable Isotope-Resolved Metabolomics (RC-SIRM)
Metabolomics Core at Mayo Clinic

more about our RCMRCs

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