Summary of Study ST002343
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001502. The data can be accessed directly via it's Project DOI: 10.21228/M8JD81 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002343 |
Study Title | The impact of myriocin and dietary serine restriction on paw skin sphingolipid diversity |
Study Summary | We analyzed paw skin polar and lipid metabolites in mice (C57BL/6J) in response to two dietary interventions. The first was: 1) low fat (LFD), 2) serine/glycine-free LFD (-SG LFD), high fat (HFD), and serine/glycine-free HFD (-SG HFD). And the second was: 1) low fat (LFD), high fat (HFD), serine/glycine-free HFD (-SG HFD), and serine/glycine-free HFD (-SG HFD) with myriocin (0.3 mg/kg every other day) treatment. The goal of the study was to determine the impact of dietary serine/glycine restriction and myriocin treatment on the hepatic lipidome. |
Institute | Salk Institute for Biological Studies |
Department | Molecular and Cell Biology Laboratory |
Laboratory | Metallo Lab |
Last Name | Handzlik |
First Name | Michal |
Address | 10010 N Torrey Pines Rd, La Jolla, California, 92037, USA |
mhandzlik@salk.edu | |
Phone | 2069601945 |
Submit Date | 2022-11-11 |
Num Groups | LFD, -SG LFD, HFD, -SG HFD, LFD+Veh, HFD+Veh, -SG HFD+Veh, -SG HFD+Myr |
Total Subjects | 47 |
Num Males | 47 |
Raw Data Available | Yes |
Raw Data File Type(s) | d |
Analysis Type Detail | LC-MS |
Release Date | 2024-01-01 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Subject:
Subject ID: | SU002432 |
Subject Type: | Mammal |
Subject Species: | Mus musculus |
Taxonomy ID: | 10090 |
Genotype Strain: | C57BL/6J |
Age Or Age Range: | 8-32-week-old |
Weight Or Weight Range: | 25-50 |
Gender: | Male |
Animal Animal Supplier: | JAX |
Animal Housing: | 5/cage |
Animal Light Cycle: | 12h dark/12 h light |
Animal Feed: | Special diets; see group labeling |
Animal Water: | Ad libitum |