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MB Sample ID: SA327796
| Local Sample ID: | M_Cefto6g_191_3 |
| Subject ID: | SU003138 |
| Subject Type: | Bacteria |
| Subject Species: | Pseudomonas aeruginosa |
| Taxonomy ID: | 287 |
| Genotype Strain: | CW41 |
| Age Or Age Range: | NA |
| Weight Or Weight Range: | NA |
| Height Or Height Range: | NA |
| Gender: | Not applicable |
| Cell Strain Details: | hypermutable clinical isolate |
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Treatment:
| Treatment ID: | TR003147 |
| Treatment Summary: | Ceftolozane-tazobactam was administered to simulate steady-state concentrations of ceftolozane predicted to occur in the epithelial lining fluid of the lung in patients with CF, following daily doses of 3 g/1.5 g and 6 g/3 g via continuous infusion (10.6 and 21.3 mg/L, respectively) (21-23). Total bacterial populations were quantified on antibiotic-free CAMHA, and resistant subpopulations on CAMHA containing ceftolozane-tazobactam (12 and 20 mg/L). |
| Treatment: | continuous infusion |
| Treatment Compound: | Ceftolozane-tazobactam |
| Treatment Dose: | 3 g and 6 g |
| Treatment Dosevolume: | 10.6 and 21.3 mg/L |
