Summary of Study ST000743

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000536. The data can be accessed directly via it's Project DOI: 10.21228/M8CQ3P This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST000743
Study TitleMetabolomics of bariatric weight loss
Study TypeMS analysis
Study SummaryHuman patients were enrolled in a bariatric weight loss clinic and followed. Patients were male and female, normoglycemic,pre-diabetic and diabetic and with and without neuropathy. One 500 ul aliquot will be submitted for both untargeted metabolomics and shotgun lipidomics.
Institute
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Emailmkachman@med.umich.edu
Phone(734) 232-8175
Submit Date2017-06-19
Num Groups7
Total Subjects3
Raw Data AvailableYes
Raw Data File Type(s)wiff
Analysis Type DetailLC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman
https://dx.doi.org/10.21228/M8CQ3P
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Project:

Project ID:PR000536
Project DOI:doi: 10.21228/M8CQ3P
Project Title:Callaghan Bariatric plasma baseline
Project Type:MS analysis
Project Summary:Obesity study with intervention
Institute:University of Michigan
Department:Neurology
Laboratory:Feldman Lab
Last Name:Feldman
First Name:Eva
Address:Ann Arbor, MI
Email:efeldman@umich.edu
Phone:734-763-7274

Subject:

Subject ID:SU000766
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Species Group:Mammals

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Gender Glycemic status Neuropathy
SA041227S00025579female diabetic Neuropathy
SA041228S00025577female diabetic Neuropathy
SA041229S00025578female diabetic Neuropathy
SA041230S00025568female diabetic Neuropathy
SA041231S00025580female diabetic no neuropathy
SA041232S00025573female diabetic no neuropathy
SA041233S00025571female diabetic no neuropathy
SA041234S00025574female diabetic no neuropathy
SA041235S00025570female normoglycemic Neuropathy
SA041236S00025581female normoglycemic no neuropathy
SA041237S00025575male diabetic Neuropathy
SA041238S00025576male diabetic no neuropathy
SA041239S00025572male pre-diabetic Neuropathy
SA041240S00025569male pre-diabetic no neuropathy
Showing results 1 to 14 of 14

Collection:

Collection ID:CO000760
Collection Summary:-

Treatment:

Treatment ID:TR000780
Treatment Summary:-

Sample Preparation:

Sampleprep ID:SP000773
Sampleprep Summary:-
Sampleprep Protocol Filename:A003_-_Untargeted_Metabolomics.pdf

Combined analysis:

Analysis ID AN001159 AN001160 AN001161 AN001162
Chromatography ID CH000817 CH000817 CH000818 CH000818
MS ID MS001054 MS001055 MS001056 MS001057
Analysis type MS MS MS MS
Chromatography type Reversed phase Reversed phase Reversed phase Reversed phase
Chromatography system Agilent Agilent Shimadzu CTO-20A Nexera X2 Shimadzu CTO-20A Nexera X2
Column Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um) Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
MS Type ESI ESI ESI ESI
MS instrument type QTOF QTOF Triple TOF Triple TOF
MS instrument name Agilent 6530 QTOF Agilent 6530 QTOF ABI Sciex 5600+ TripleTOF ABI Sciex 5600+ TripleTOF
Ion Mode POSITIVE NEGATIVE NEGATIVE POSITIVE
Units peak area normalized peak area normalized peak area normalized peak area normalized

Chromatography:

Chromatography ID:CH000817
Instrument Name:Agilent
Column Name:Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
Chromatography Type:Reversed phase
  
Chromatography ID:CH000818
Instrument Name:Shimadzu CTO-20A Nexera X2
Column Name:Waters Acquity HSS T3 (50 x 2.1mm,1.8um)
Column Temperature:55
Flow Rate:0.400uL/min
Solvent A:40% acetonitrile/60% water; 10 mM ammonium acetate
Solvent B:10% acetonitrile/5% water/85% isopropanol; 10 mM ammonium acetate
Chromatography Type:Reversed phase

MS:

MS ID:MS001054
Analysis ID:AN001159
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:POSITIVE
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
  
MS ID:MS001055
Analysis ID:AN001160
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:NEGATIVE
Analysis Protocol File:A003_-_Untargeted_Metabolomics.pdf
  
MS ID:MS001056
Analysis ID:AN001161
Instrument Name:ABI Sciex 5600+ TripleTOF
Instrument Type:Triple TOF
MS Type:ESI
Ion Mode:NEGATIVE
Analysis Protocol File:A004_-_Shotgun_Lipidomics.pdf
  
MS ID:MS001057
Analysis ID:AN001162
Instrument Name:ABI Sciex 5600+ TripleTOF
Instrument Type:Triple TOF
MS Type:ESI
Ion Mode:POSITIVE
Analysis Protocol File:A004_-_Shotgun_Lipidomics.pdf
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