Summary of Study ST001737

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001111. The data can be accessed directly via it's Project DOI: 10.21228/M83D7M This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001737
Study Title1H HRMAS NMR Spectroscopy based Metabolomics of Urinary Bladder Tissues from NMIBC Patients
Study TypeNMR Based Metabolomics
Study SummaryApplication of 1H HRMAS NMR Spectroscopy to study malignancy induced metabolomic changes in urinary bladder tissues from 26 NMIBC patients. Predict the possible biomarker of NMIBC in urinary bladder tissues.
Institute
Centre of Biomedical Research, Lucknow, India
DepartmentDepartment of Radiology
LaboratoryNMR Based Metabolomics
Last NameRoy
First NameRaja
AddressCentre of Biomedical Research, Lucknow, India 226014
Emailrajaroy28@gmail.com
Phone+919005095427
Submit Date2021-03-22
Num Groups2
Total Subjects26 (n=26, malignant, and n=26, benign)
Analysis Type DetailNMR
Release Date2021-04-20
Release Version1
Raja Roy Raja Roy
https://dx.doi.org/10.21228/M83D7M
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Project:

Project ID:PR001111
Project DOI:doi: 10.21228/M83D7M
Project Title:1H HRMAS NMR Spectroscopy based Metabolomics of Urinary Bladder Tissues from NMIBC Patients
Project Type:NMR Based Metabolomics
Project Summary:Application of 1H HRMAS NMR Spectroscopy to study malignancy induced metabolomic changes in urinary bladder tissues from 26 NMIBC patients. Predict the possible biomarker of NMIBC in urinary bladder tissues.
Institute:Centre of Biomedical Research, Lucknow
Department:Department of Radiology
Laboratory:NMR Based Metabolomics
Last Name:Roy
First Name:Raja
Address:Centre of Biomedical Research, Lucknow, India 226014
Email:rajaroy28@gmail.com
Phone:+919005095427
Contributors:Anup Paul, Raja Roy, Akshay Anand, Kushagra Gaurav, Mala Sagar, Abhinav A. Sonkar

Subject:

Subject ID:SU001814
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Age Or Age Range:57.42 ± 4.1 years
Gender:Not applicable

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Histopathological_Status
SA162874Patient_10_Benign1
SA162875Patient_9_Benign1
SA162876Patient_11_Benign1
SA162877Patient_12_Benign1
SA162878Patient_13_Benign1
SA162879Patient_8_Benign1
SA162880Patient_7_Benign1
SA162881Patient_3_Benign1
SA162882Patient_4_Benign1
SA162883Patient_5_Benign1
SA162884Patient_6_Benign1
SA162885Patient_14_Benign1
SA162886Patient_16_Benign1
SA162887Patient_23_Benign1
SA162888Patient_22_Benign1
SA162889Patient_24_Benign1
SA162890Patient_25_Benign1
SA162891Patient_26_Benign1
SA162892Patient_21_Benign1
SA162893Patient_20_Benign1
SA162894Patient_2_Benign1
SA162895Patient_17_Benign1
SA162896Patient_18_Benign1
SA162897Patient_19_Benign1
SA162898Patient_15_Benign1
SA162899Patient_1_Benign1
SA162900Patient_10_Malignant2
SA162901Patient_9_Malignant2
SA162902Patient_11_Malignant2
SA162903Patient_12_Malignant2
SA162904Patient_13_Malignant2
SA162905Patient_8_Malignant2
SA162906Patient_7_Malignant2
SA162907Patient_3_Malignant2
SA162908Patient_2_Malignant2
SA162909Patient_4_Malignant2
SA162910Patient_5_Malignant2
SA162911Patient_6_Malignant2
SA162912Patient_14_Malignant2
SA162913Patient_15_Malignant2
SA162914Patient_23_Malignant2
SA162915Patient_22_Malignant2
SA162916Patient_24_Malignant2
SA162917Patient_25_Malignant2
SA162918Patient_26_Malignant2
SA162919Patient_21_Malignant2
SA162920Patient_20_Malignant2
SA162921Patient_16_Malignant2
SA162922Patient_17_Malignant2
SA162923Patient_18_Malignant2
SA162924Patient_19_Malignant2
SA162925Patient_1_Malignant2
Showing results 1 to 52 of 52

Collection:

Collection ID:CO001807
Collection Summary:Urinary Bladder Tissue (UBT) specimens collected from 26 patients who have undergone surgical treatment for NMIBC at KGMU, Lucknow.Informed consent was obtained from all the patients and protocols were approved by KGMU Ethical Committee. On the basis of visual screening by the surgeons tissue specimens includes NMIBC lesions and adjacent tissues of urinary bladder. The tissues specimens were snap frozen in liquid nitrogen during surgical resection and stored in cryo-vials at -80 degree Centigrade till Spectral recording.
Sample Type:Tissue Specimen

Treatment:

Treatment ID:TR001827
Treatment Summary:Stored urinary bladder tissues were thawed to room temperature. Then saline water used to washed these specimens.

Sample Preparation:

Sampleprep ID:SP001820
Sampleprep Summary:The wet tissues were dissected to weighted of 34 mg then transferred into 50 μl ZrO2 rotor.

Analysis:

Analysis ID:AN002828
Laboratory Name:Division of SAIF, CSIR-Central Drug Research Institute, Lucknow
Analysis Type:NMR

NMR:

NMR ID:NM000204
Analysis ID:AN002828
Instrument Name:Bruker Fallandden
Instrument Type:FT-NMR
NMR Experiment Type:1D-1H
Standard Concentration:0.7697 mM
Spectrometer Frequency:400 MHz
NMR Probe:HRMAS dual probehead
NMR Solvent:D2O
NMR Tube Size:4mm ZrO2 rotor of 50 ?l capacity
Pulse Sequence:CPMG, NOESY
Water Suppression:PR
Receiver Gain:2050
Temperature:281 ± 0.5 K
Number Of Scans:128
Dummy Scans:4
Relaxation Delay:5.992s
Spectral Width:8223.685 Hz
Num Data Points Acquired:32K
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