Data for (Study ST000843)

(Analysis AN001364)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7F8F9F10F11F12F13F14F15F16F17F18
11_12-DiHETrE 1.2648 0.6771 1.0409 2.4512 0.5708 0.3805 2.6023 0.7051 1.6117 3.2794 0.4141 0.6380 0.3917 0.7387 0.2518 0.0672 0.2574 0.2350
11(12)-EpETE NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA
11(12)-EpETrE 1.3465 0.9265 0.6487 1.8942 0.6889 0.7403 2.0377 0.6969 2.2577 3.8989 1.0245 0.5347 0.5139 0.2377 0.1991 0.3597 0.2505 0.2184
11-HETE 0.7629 0.6109 0.9019 3.3861 1.1783 0.4470 1.2386 0.5558 1.6601 3.7556 0.5950 1.0731 0.2612 0.2220 0.2046 0.1828 0.2177 0.2003
12_13-DiHODE NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA
12_13-DiHOME 1.3869 1.0421 0.7696 1.9823 1.1670 0.5910 1.5927 1.0674 0.4802 3.0651 1.1426 0.4116 0.4933 0.4153 0.4388 0.6737 0.4905 0.4379
12(13)-Ep-9-KODE 0.1845 0.2432 0.1825 7.7156 1.2496 0.3525 0.1291 0.2540 1.8620 1.9422 0.3220 0.2342 0.0704 0.0818 0.0608 0.1371 0.1308 0.0690
12(13)-EpODE 1.0635 0.5815 0.9692 2.5308 1.1397 0.7808 0.9423 2.1179 0.7000 2.5128 0.7000 NA 0.1615 0.4487 0.2154 0.2692 0.3410 0.1974
12(13)-EpOME 1.3613 0.8839 0.8996 1.6149 0.9688 0.7275 0.7822 0.3039 0.6514 1.6916 0.3482 0.4372 1.3064 0.8801 0.9954 1.5955 1.0850 1.1967
12-HEPE 1.5905 0.7042 0.5180 2.2488 1.5608 0.2078 1.7443 0.1282 1.1278 1.6593 0.3454 0.4148 NA NA NA NA NA NA
12-HETE 1.2633 0.9763 0.8392 2.0967 1.8191 0.1768 1.7864 0.1450 2.3819 2.5920 0.7045 0.5396 0.3278 0.3266 0.3498 0.5377 0.2505 0.3652
13-HODE 0.7298 0.5739 1.2854 3.6154 1.1604 0.4342 1.0531 0.3689 1.7170 2.9572 0.5193 0.5471 0.3138 0.2816 0.2711 0.3875 0.2536 0.2898
13-HOTE 0.4595 0.3614 3.7967 3.4311 1.2683 0.6312 0.7629 0.3718 1.0869 1.0430 0.4363 0.2130 0.4453 0.0968 0.0361 0.2672 0.0349 0.0155
13-KODE 0.2655 0.1448 0.1723 6.5878 0.8830 0.2458 0.1527 0.0786 1.1607 6.0865 0.1239 0.1420 0.0894 0.0325 0.0604 0.1048 0.0725 0.1021
14_15-DiHETE NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA
14_15-DiHETrE 1.0500 0.9286 1.5286 1.6929 1.1714 0.1714 1.0286 1.3286 0.8714 2.0000 1.0714 0.9000 0.7429 0.6000 0.3857 0.6143 0.6286 0.3857
14(15)-EpETE NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA
14(15)-EpETrE 1.4709 0.7442 0.8624 1.9858 0.7695 0.7526 2.0915 0.3353 1.6211 3.9224 0.5162 0.6767 0.6923 0.3594 0.2822 0.4728 0.3980 0.3594
14-HDoHE 1.7874 1.0287 0.8355 2.4892 1.3215 0.1963 2.6460 0.1113 1.9521 2.1903 0.5493 0.5846 0.4780 0.3345 0.2456 0.5779 0.1380 0.3067
15_16-DiHODE 1.4113 0.6312 1.0193 2.0385 0.7514 0.9997 1.1957 0.5684 0.5423 3.7373 0.6762 0.4802 0.6076 0.0980 0.1307 0.4051 0.6860 0.2548
15(16)-EpODE 0.6417 0.3614 0.9585 0.8204 0.6701 0.8204 0.6051 0.4873 0.5077 3.8257 0.2559 NA NA NA NA NA NA NA
15-deoxy PGJ2 1.1027 0.8427 1.1117 1.1296 1.0623 1.2103 0.6656 0.9144 0.9906 1.1430 0.8382 0.8674 NA NA NA NA NA NA
15-HEPE 0.8616 0.3998 0.8250 2.2272 1.0249 0.2872 1.3346 0.2661 1.3093 2.1061 0.5702 0.1985 NA NA NA NA NA NA
15-HETE 1.4874 0.4957 0.6229 4.4285 1.1049 0.5902 1.2781 0.2161 1.8914 5.0172 0.3222 0.4813 0.2218 0.1937 0.1202 0.2026 0.0984 0.0952
15-KETE 0.6675 0.1370 0.3195 1.2613 0.4761 0.2799 0.1655 0.0304 0.5198 6.9450 0.0672 0.1466 NA NA NA NA NA NA
15-Keto PGE2 1.1732 0.4791 0.3572 1.6991 1.2714 0.3882 1.0521 0.6896 0.1196 3.6781 0.8058 0.0423 NA NA NA NA NA NA
16(17)-EpDPE NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA
17_18-DiHETE NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA
17(18)-EpETE NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA
17-HDoHE 0.6768 0.9462 0.2972 3.3036 1.0775 0.5726 1.0822 0.1789 0.7532 0.9436 0.4555 0.5392 NA NA NA NA NA NA
19_20-DiHDoPA 1.1522 0.7155 0.7113 1.3732 1.7818 0.6208 1.2311 1.1084 1.4311 2.7289 1.4241 0.3999 0.5823 0.1368 0.3016 0.4630 0.3472 0.2631
19(20)-EpDPE 1.4745 0.7919 0.7056 1.6233 0.7334 1.9906 0.4252 1.0970 1.2449 3.0136 1.0045 0.4992 0.5916 0.2280 0.0370 0.3328 NA 0.0462
20-HETE 3.2333 0.2536 0.7467 0.5283 0.6199 1.0566 NA NA NA NA NA NA 1.0073 1.2891 0.3593 2.4021 0.4015 0.7608
4-HDoHE 1.2301 0.4365 1.4705 2.7110 1.3614 1.0254 0.8008 0.2904 2.1212 2.5631 0.6511 0.2354 0.1082 0.0812 0.0379 0.0460 0.1380 0.0054
5_15-DiHETE 0.0409 0.9632 1.8198 0.1612 1.4275 1.1012 0.0673 1.3259 1.4718 0.0204 0.9581 1.5487 NA NA NA NA NA NA
5_6-DiHETrE NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA
5-HEPE NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA
5-HETE 0.7144 0.4762 2.8764 1.2820 0.4093 1.0272 3.2195 0.2221 2.0680 2.6770 0.7808 0.4908 0.3674 0.1531 0.1636 0.1288 0.4584 0.1732
5-KETE 0.2969 0.2232 0.5244 1.9043 0.8007 0.5091 0.5526 0.1734 1.8197 11.1687 0.2514 0.3522 0.0846 0.0631 0.0639 0.0614 0.2149 0.1444
6-keto PGF1a 0.6708 0.6642 0.4878 4.3876 2.6619 0.5164 0.3280 0.1828 0.8092 1.4663 0.8467 0.3987 0.2237 0.2041 0.3578 0.1099 0.3701 0.4105
6-trans-LTB4 0.6548 0.3390 3.7135 1.3622 0.3297 1.0619 1.7553 0.1641 1.0696 1.1470 0.3932 0.2229 NA NA NA NA 0.3390 NA
8_15-DiHETE 0.9182 0.7940 0.6787 2.3186 0.9060 1.2746 0.4019 1.1869 0.9174 1.1414 0.5910 1.0472 NA NA NA NA NA NA
8_9-DiHETrE NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA
8(9)-EpETrE 1.2582 0.5722 0.4902 2.1789 0.8052 1.0508 1.5983 0.2268 2.7773 5.2501 0.5871 0.1631 0.3138 0.1491 0.1553 0.2268 0.1864 0.2516
8-HETE 0.5293 0.2203 0.8919 4.7876 1.0670 1.1013 1.1883 0.2583 1.8980 2.7355 0.3100 0.2746 0.1414 0.1414 0.0272 0.1088 0.0489 0.0272
9_10-DiHODE 1.5080 0.6724 0.9889 2.6370 1.4009 0.7087 1.1619 0.7087 0.2143 2.5216 0.7417 0.0989 0.1483 0.0494 NA 0.0989 0.0494 NA
9_10-DiHOME 1.3879 1.0275 0.8498 1.9481 1.0603 0.5956 1.4330 1.0099 0.5474 2.8268 1.0380 0.4043 0.5976 0.5033 0.5364 0.8236 0.5204 0.5413
9_10-e-DiHO 1.0533 1.0149 1.3858 1.4113 0.9018 0.9565 0.8605 0.9828 0.6160 1.3500 0.6364 0.7027 NA NA NA NA NA NA
9_10-EpO 1.1790 1.1684 1.3390 1.1218 0.8636 1.1329 0.8439 1.0885 0.6685 1.1500 0.4957 0.9343 NA NA NA NA NA NA
9(10)-EpODE 0.7451 0.4221 0.5295 3.7359 0.8183 0.3184 0.6850 0.6356 0.9133 5.9920 0.6294 0.5184 0.3147 0.0679 0.1296 0.1851 0.1728 0.1851
9(10)-EpOME 1.3847 0.7576 0.8474 1.9127 1.0230 0.7145 0.7751 0.2528 0.6886 1.9359 0.3687 0.3789 1.2620 0.8097 0.9361 1.3912 1.0454 1.1547
9-HEPE NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA
9-HETE 0.6644 0.4639 1.2657 2.9856 0.9004 0.7129 0.3370 0.2635 0.9230 1.9608 0.5722 0.4267 NA NA NA NA NA NA
9-HODE 0.7611 0.5200 0.9863 4.1722 1.1496 0.4672 0.8717 0.4671 1.5510 3.1094 0.5756 0.5705 0.2584 0.1937 0.2272 0.3071 0.2426 0.2252
9-HOTE 0.5956 0.4947 1.5556 3.7817 0.8787 0.5272 0.3417 0.4361 0.9243 1.2888 0.2213 0.4003 NA NA NA NA NA NA
9-KODE 0.2968 0.1784 0.2453 6.6462 0.8936 0.2423 0.2328 0.1281 1.1911 5.2026 0.1927 0.1491 0.1337 0.0814 0.1101 0.1569 0.1425 0.1474
Lipoxin A4 0.6713 1.0779 0.9442 0.7163 0.9551 1.0070 NA NA NA NA NA NA 0.9688 1.1161 0.8105 1.2580 0.9879 1.2826
LTB4 1.1348 0.3075 2.3817 1.3426 0.2085 1.3075 5.7538 0.4079 0.8940 2.0072 0.7266 0.5860 0.3602 0.1654 0.1857 0.1390 0.7459 0.3136
LTB5 1.3167 0.4938 1.7007 1.0698 0.4663 1.2344 2.9626 0.6584 0.4389 1.1247 0.6309 0.4938 NA NA NA NA NA NA
PGD2 0.4269 0.6346 0.8542 0.6216 0.3856 0.2457 1.0951 1.9433 1.7389 1.3718 3.2628 1.7634 0.8306 1.2198 1.5541 0.5076 1.3694 0.7840
PGE1 0.7006 1.4573 1.1179 0.4598 1.5093 0.5733 0.6240 1.3574 1.8664 0.5336 1.6310 5.1394 0.2572 0.5145 0.5254 0.2244 0.2737 0.1916
PGE2 0.9012 1.2552 1.3537 0.7136 1.6177 0.5524 1.2466 0.7593 1.4385 1.4923 1.2389 2.9449 0.4524 0.6625 0.6053 0.3237 0.3825 0.2345
PGF2a 0.9811 1.0187 2.1368 1.4658 0.8358 0.9894 1.5442 0.2467 0.8459 2.3869 0.5106 1.1144 0.5367 0.4505 0.6277 0.4928 0.3909 0.3599
Resolvin D1 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA
SUM-TriHOME 0.9937 1.0155 1.3713 1.9270 1.1129 0.8048 1.6451 1.2935 1.5750 2.2446 1.1773 0.9550 0.2054 0.1972 0.1692 0.2299 0.1746 0.1876
TXB2 1.1137 0.8056 1.1170 1.2912 2.5863 0.6784 1.3122 0.4531 1.4406 1.2922 0.7929 0.5162 0.5793 0.2940 0.7577 0.3109 0.8285 0.3538
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Factors:

F1Treatment:Control | Lung:Left Lung | Time point (day):-
F2Treatment:Control | Lung:Left Lung | Time point (day):12
F3Treatment:Control | Lung:Left Lung | Time point (day):8
F4Treatment:Control | Lung:Right Lung | Time point (day):-
F5Treatment:Control | Lung:Right Lung | Time point (day):12
F6Treatment:Control | Lung:Right Lung | Time point (day):8
F7Treatment:Pravastatin | Lung:Left Lung | Time point (day):-
F8Treatment:Pravastatin | Lung:Left Lung | Time point (day):12
F9Treatment:Pravastatin | Lung:Left Lung | Time point (day):8
F10Treatment:Pravastatin | Lung:Right Lung | Time point (day):-
F11Treatment:Pravastatin | Lung:Right Lung | Time point (day):12
F12Treatment:Pravastatin | Lung:Right Lung | Time point (day):8
F13Treatment:Simvastatin | Lung:Left Lung | Time point (day):-
F14Treatment:Simvastatin | Lung:Left Lung | Time point (day):12
F15Treatment:Simvastatin | Lung:Left Lung | Time point (day):8
F16Treatment:Simvastatin | Lung:Right Lung | Time point (day):-
F17Treatment:Simvastatin | Lung:Right Lung | Time point (day):12
F18Treatment:Simvastatin | Lung:Right Lung | Time point (day):8
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