Funding Opportunities

See also our P&F and Funded Research pages.

Current Funding Opportunities

2017 Call for Pilot and Feasibility Project Applications

Pilot and Feasibility Projects

The six Regional Comprehensive Metabolomics Research Cores (RCMRCs) are accepting applications for exploratory biomedical research projects utilizing metabolomics technology. These "Pilot and Feasibility (P&F) studies" are intended to provide opportunities for investigators to advance basic, clinical and translational biomedical science by incorporating metabolomic technologies into their research. The awards are intended to support projects that will provide preliminary data for new extramural proposal submission. Application deadline: March 16, 2017.

Eligibility

All basic, translational, or clinical investigators who are eligible to apply as a PI for NIH grants are invited to apply. Early stage investigators or those new to the metabolomics field are especially encouraged to apply.

Application Procedures

Application information for P&F studies at the Michigan Regional Comprehensive Metabolomics Research Core
Application information for P&F studies at the NIH West Coast Metabolomics Center at UC Davis
Application information for P&F studies at the NIH Eastern Regional Comprehensive Metabolomics Resource Core (ERCMRC)
Application information for P&F studies at the Southeast Center for Integrated Metabolomics
Application information for P&F studies at the Metabolomics Core at Mayo Clinic
Application information for P&F studies at the Resource Center for Stable Isotope-Resolved Metabolomics

Learn More about the RCMRCs

Michigan Regional Comprehensive Metabolomics Research Core (MRC)2
NIH West Coast Metabolomics Center at UC Davis
Eastern Regional Comprehensive Metabolomics Resource Core (ERCMRC)
Southeast Center for Integrated Metabolomics (SECIM)
Metabolomics Core at Mayo Clinic
Resource Center for Stable Isotope-Resolved Metabolomics (RC-SIRM)

See also the NIH Common Fund Metabolomics announcement .

Past Funding Opportunities

Novel Analytical Approaches for Metabolomics Data (R03)

The National Institutes of Health (NIH) has developed a Common Fund initiative to foster collaboration between computational scientists, metabolomics experts, and biomedical researchers in developing, piloting, and/or validating novel bioinformatic approaches that address current analytical hurdles in metabolomics data. A goal of providing powerful approaches that will be useful to biomedical researchers, as well as bioinformaticians, is particularly encouraged. Projects are not intended to supplement ongoing metabolomics analyses, but to provide a tool for broader use by the biomedical research community. Projects are expected to use existing, publicly available metabolomics data and complement the efforts and resources of the Common Fund Metabolomics Program.

Letter of intent due January 14, 2017
Application due February 14, 2017

See the Funding Opportunity Announcement (FOA) for further details.

The NCI SBIR Program recently announced 15 new contract funding opportunities in a range of novel technology areas, including NIH/NCI 364: Methods and Software for Integration of Cancer Metabolomic Data with Other –Omic and Imaging Data. The deadline for receipt of all FY2017 contract topic proposals is October 21, 2016 by 5:00 PM ET.

The goal of this project is to develop new and innovative bioinformatic methods to integrate metabolite data with and other –omics and/or cancer imaging data and ultimately design scalable software tool(s) that apply these methods to automate the integration of the data.

In Phase I, offerors should provide evidence that bioinformatic methods integrating identified metabolite data with other –omics and/or imaging data have been effectively developed, can be implemented across data inputs from at least one analytical technology used in metabolomics and at least one analytical technology used in genomics, proteomics, epigenomics, transcriptomics, or cancer imaging; and demonstrate readiness to proceed to Phase II. Additionally, phase I should be used to demonstrate the framework for scalable software tool(s) that apply the bioinformatic methods to automate the integration of metabolite and other –omics and/or cancer imaging data. In Phase II, offerors should expand the bioinformatic methods to include unidentified metabolite peaks, in addition to identified metabolite data, and demonstrate metabolite data integration other –omics and/or cancer imaging data.

Additional information and contacts:

NCI SBIR Development Center Website for 2017 Contract Topics

PHS 2017-1 SBIR Solicitation (NIH and CDC SBIR Contract Topics) (PDF)

Point of Contact for Specific Questions About RFP Solicitation

Contracting Officers:
Any small business that intends to submit an SBIR contract proposal under this Solicitation should provide the appropriate contracting officer(s) with early, written notice of its intent, giving its name, address, e-mail, telephone, and topic number(s). If a topic is modified or canceled before the Solicitation closes, only those companies that have expressed such intent will be notified.

See the funding notice for further details.

2016 Call for Pilot and Feasibility Project Applications from Regional Comprehensive Metabolomics Research Cores

Pilot and Feasibility Projects

The six Regional Comprehensive Metabolomics Research Cores (RCMRCs) are accepting applications for exploratory biomedical research projects utilizing metabolomics technology. These "Pilot and Feasibility (P&F) studies" are intended to provide opportunities for investigators to advance basic, clinical and translational biomedical science by incorporating metabolomic technologies into their research. Awards are intended to support projects that will provide preliminary data for new extramural proposal submission. Application deadline: March 15, 2016.

Eligibility

All basic, translational, or clinical investigators who are eligible to apply as a PI for NIH grants are invited to apply. Early stage investigators or those new to the metabolomics field are especially encouraged to apply.

Application Procedures

Application information for P&F studies at the Michigan Regional Comprehensive Metabolomics Research Core
Application information for P&F studies at the NIH West Coast Metabolomics Center at UC Davis
Application information for P&F studies at the NIH Eastern Regional Comprehensive Metabolomics Resource Core at RTI International
Application information for P&F studies at the Southeast Center for Integrated Metabolomics
Application information for P&F studies at the Metabolomics Core at Mayo Clinic
Application information for P&F studies at the Resource Center for Stable Isotope-Resolved Metabolomics

Learn More about the RCMRCs

Michigan Regional Comprehensive Metabolomics Research Core (MRC)2
NIH West Coast Metabolomics Center at UC Davis
NIH Eastern Regional Comprehensive Metabolomics Resource Core at RTI International (RTI RCMRC)
Southeast Center for Integrated Metabolomics (SECIM)
Metabolomics Core at Mayo Clinic
Resource Center for Stable Isotope-Resolved Metabolomics (RC-SIRM)

Metabolomics Data Analysis (R03)

The purpose of this small research grant Funding Opportunity Announcement (FOA) is to foster collaboration between bioinformaticians, metabolomics experts, and/or biomedical researchers in efforts to improve the ability to analyze metabolomics data to address biomedical questions. It is also expected that these grants would complement the current efforts of the Common Fund Metabolomics Program and maximize the value of existing metabolomics databases and resources.

Administrative Supplements for Collaborative Activities to Promote Metabolomics Research (PA-16-005)

These administrative supplements aim to support collaborative, multi-disciplinary research using metabolomics and to help expand the cadre of investigators experienced in metabolomics study design, analytical methodology, and data interpretation. These supplements will provide funds to current NIH-funded research projects for new collaborations between basic or clinical researchers and metabolomics experts to pursue biomedical studies requiring a metabolomics approach within the scope of the parent grant.

Read the Funding Opportunity Announcements (FOAs).

Funding Opportunity Announcements (FOAs) for the Molecular Transducers of Physical Activity in Humans Program

Funding Opportunity Announcements (FOAs) for the Molecular Transducers of Physical Activity in Humans Program have been released. These FOAs invite applications for the six scientific components of the Molecular Transducers of Physical Activity Consortium (MoTrPAC). The MoTrPAC is a national research consortium designed to discover and perform preliminary characterization of the range of molecular transducers (the ‘molecular map’) that underlie the effects of physical activity in humans.

Read the Funding Opportunity Announcements (FOAs).

Notice of Intent to Publish a Funding Opportunity Announcement for NLM Institutional Grants for Research Training in Biomedical Informatics and Data Science (T15)

The National Library of Medicine (NLM) intends to publish a Funding Opportunity Announcement (FOA) to solicit applications for institutional training programs for research careers in biomedical informatics and data science.

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. 

The FOA is expected to be published in the winter of 2016 with an expected application due date in the spring of 2016.

Read the Notice of Intent to Publish a Funding Opportunity Announcement

NIH/NCI 341: Development of Metabolomics Data Integration Methods and Software

The purpose of this topic is to support the development of new and innovative methods to integrate metabolite data across analytical technologies and laboratory platforms, and in turn, design software tool(s) applying these methods for data integration. This topic aims to 1) develop bioinformatic methods to integrate metabolite data across various laboratory platforms and analytical technologies, including liquid-chromatography-mass spectrometry (LC-MS), gas chromatography-mass spectrometry (GC-MS), and NMR; and 2) develop scalable software tool(s) to automate these methods for use by the cancer and overall public health research communities.

Responses to this topic are expected to address the development of efficient bioinformatic methods to:

  1. Demonstrate bioinformatic methods for the integration of metabolite data across different laboratory platforms and analytical technologies with high accuracy;
  2. Store metabolite data from the different data sources in databases that can be easily used for data integration and quality control protocols;
  3. Implement valid quality control (QC) checks; and
  4. Appropriately secure data at each stage of transfer and storage.

An essential task for each proposal is the development of bioinformatic tools in the form of scalable software that can be used by the research community at-large to automate complex data integration tasks for metabolomics data sources.

Read the Funding Opportunity Announcement

Consortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer

These U01 funding opportunitities are for the establishment of a clinical consortium, composed of one Coordination and Data Management Center (CDMC) and up to 9 Clinical Centers (CC), to conduct studies on chronic pancreatitis (CP) and factors that increase the risk of pancreatic cancer in patients (children and adults) with CP, pancreatogenic (type 3c) diabetes (T3cDM) and in patients with newly diagnosed diabetes.

The Consortium will form multi-disciplinary teams composed of members from the CCs and CDMC to undertake a comprehensive clinical, epidemiological and biological characterization of patients with CP (including those with Acute Recurrent Pancreatitis, ARP) to gain insight into the pathophysiology of chronic pancreatitis and its sequela: chronic pain, pancreatic insufficiency, T3cDM and the diabetes/pancreatic cancer association. The teams will also undertake studies on the development of pancreatic cancer in newly diagnosed diabetic patients.

  • Clinical Centers

    To achieve the goal of a comprehensive characterization of evolving chronic pancreatitis and pancreatic cancer, each CC should include researchers and clinicians with multi-disciplinary expertise. Research CCs will be expected to share results freely within Consortium and to develop trans-Consortium collaborative projects that make use of the combined expertise and technological capabilities present in all of the CCs.

    Read the Funding Opportunity Announcement.

  • Coordination and Data Management Center

    To achieve the goal of a comprehensive characterization of evolving chronic pancreatitis and pancreatic cancer, the Coordinating and Data Management Center (CDMC) will take on the administrative and data collection/analysis functions and will be responsible for the conduct of all of the ongoing and future studies of the CCs.

    Read the Funding Opportunity Announcement.

Children's Health Exposure Analysis Resource (CHEAR)

NIEHS is establishing an infrastructure, the Children's Health Exposure Analysis Resource (CHEAR), to provide the extramural research community access to laboratory and statistical analyses to add or expand the inclusion of environmental exposures in their research. CHEAR is being solicited through three FOAs

  • National Exposure Assessment Laboratory Network

    Each laboratory center (defined in this FOA as a Hub) within the network will provide analysis of environmental and endogenous exposures through both targeted and untargeted approaches. Each Hub will also provide analyses of biological response indicators such as DNA damage, oxidative stress, immune/inflammation indicators and other molecular markers. Hubs will incorporate a developmental core to develop novel measures for exposures and responses, expanding the number of current, commonly measured analytes, and developing new methods for detecting analytes in other biological matrices, in addition to serum, plasma or urine.

    Read the Funding Opportunity Announcement

  • Data Repository, Analysis and Science Center

    The Data Center will provide intellectual and logistical support for the maintenance, analysis, interpretation, curation, and reuse of data generated by CHEAR in support of extramural research projects. The Data Center will provide two distinct services to the extramural community. The Center will support statistical consultation and perform statistical analyses for studies using the CHEAR infrastructure including the development and dissemination of new statistical methods and informatics tools. In addition, the Data Center will develop and manage an exposure data repository and associated data science resources. The ultimate goal is maximizing potential use and impact of exposure data both within and outside of CHEAR.

    Read the Funding Opportunity Announcement

  • Coordinating Center

    The CHEAR Coordinating Center (U24) will serve as the administrative hub and external access point for CHEAR, managing the flow of materials, data, and analyses between CHEAR units and participating investigators. In addition, the coordinating center will also support administrative functions such as convening steering committee and CHEAR meetings, and organize communication and outreach activities.

    Read the Funding Opportunity Announcement.

Metabolomics Core for the Undiagnosed Diseases Network

This Funding Opportunity Announcement (FOA) is to establish a Metabolomics Core to augment clinical and laboratory findings of the Undiagnosed Diseases Network (UDN) and to assist the Network in the diagnosis of patients with undiagnosed diseases.

Read the Funding Opportunity Announcement.

2015 Call for Pilot and Feasibility Project Applications from Regional Comprehensive Metabolomics Research Cores

Pilot and Feasibility Projects

The six Regional Comprehensive Metabolomics Research Cores (RCMRCs) are accepting applications for exploratory biomedical research projects utilizing metabolomics technology. These "Pilot and Feasibility (P&F) studies" are intended to provide opportunities for investigators to advance basic, clinical and translational biomedical science by incorporating metabolomic technologies into their research. Awards are intended to support projects that will provide preliminary data for new extramural proposal submission. The application deadline: March 16, 2015.

Eligibility

All basic, translational, or clinical investigators who are eligible to apply as a PI for NIH grants are invited to apply. Early stage investigators or those new to the metabolomics field are especially encouraged to apply.

Application Procedures

Application information for P&F studies at the Michigan Regional Comprehensive Metabolomics Research Core
Application information for P&F studies at the NIH West Coast Metabolomics Center at UC Davis
Application information for P&F studies at the NIH Eastern Regional Comprehensive Metabolomics Resource Core at RTI International
Application information for P&F studies at the Southeast Center for Integrated Metabolomics
Application information for P&F studies at the Metabolomics Core at Mayo Clinic
Application information for P&F studies at the Resource Center for Stable Isotope-Resolved Metabolomics

Learn More about the RCMRCs

Michigan Regional Comprehensive Metabolomics Research Core (MRC)2
NIH West Coast Metabolomics Center at UC Davis
NIH Eastern Regional Comprehensive Metabolomics Resource Core at RTI International (RTI RCMRC)
Southeast Center for Integrated Metabolomics (SECIM)
Metabolomics Core at Mayo Clinic
Resource Center for Stable Isotope-Resolved Metabolomics (RC-SIRM)

Collaborative Activities to Promote Metabolomics Research

This FOA supports supplemental funds to current NIH-funded research projects for new interactive collaborations between basic or clinical researchers and metabolomics experts to add a metabolomics approach to the existing Research Strategy for the project.

Read the Funding Opportunity Announcement.

Information about the FOA is also listed on the NIH Common Fund Metabolomics Funding Opportunities page in tabular format: http://commonfund.nih.gov/Metabolomics/grants.

2014 Call for Pilot and Feasibility Project Applications from Regional Comprehensive Metabolomics Research Cores

Pilot and Feasibility Projects

The six Regional Comprehensive Metabolomics Research Cores (RCMRCs) are accepting applications for exploratory biomedical research projects utilizing metabolomics technology. These Pilot and Feasibility studies (P&F) are intended to provide opportunities for investigators to advance basic, clinical and translational biomedical science by incorporating metabolomic technologies into their research. These awards are intended to support projects that will provide preliminary data for new extramural proposal submission. The application deadline is March 15, 2014.

Eligibility

All basic, translational, or clinical investigators who are eligible to apply as a PI for NIH grants are invited to apply. Early stage investigators or those new to the metabolomics field are especially encouraged to apply.

Application Procedures

Application information for P&F studies at the Michigan Regional Comprehensive Metabolomics Research Core
Application information for P&F studies at the NIH West Coast Metabolomics Center at UC Davis
Application information for P&F studies at the NIH Eastern Regional Comprehensive Metabolomics Resource Core at RTI International
Application information for P&F studies at the Southeast Center for Integrated Metabolomics
Application information for P&F studies at the Metabolomics Core at Mayo Clinic
Application information for P&F studies at the Resource Center for Stable Isotope-Resolved Metabolomics

Learn More about the RCMRCs

Michigan Regional Comprehensive Metabolomics Research Core (MRC)2
NIH West Coast Metabolomics Center at UC Davis
NIH Eastern Regional Comprehensive Metabolomics Resource Core at RTI International (RTI RCMRC)
Southeast Center for Integrated Metabolomics (SECIM)
Metabolomics Core at Mayo Clinic
Resource Center for Stable Isotope-Resolved Metabolomics (RC-SIRM)

Administrative Supplements for Collaborative Activities to Promote Metabolomics Research

These administrative supplements aim to support collaborative, multi-disciplinary research using metabolomics and to help expand the cadre of investigators experienced in metabolomics study design, analytical methodology, and data interpretation. These supplements will provide funds to current NIH-funded research projects for new collaborations between basic or clinical researchers and metabolomics experts to pursue biomedical studies requiring a metabolomics approach within the scope of the parent grant.

http://grants.nih.gov/grants/guide/pa-files/PA-14-003.html

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Funding Opportunities
2017 Call for Pilot and Feasibility Project Applications

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Regional Comprehensive Metabolomics Resource Cores (RCMRC)s
Michigan Regional Comprehensive Metabolomics Resource Core (MRC)2
NIH West Coast Metabolomics Center at UC Davis
Eastern Regional Comprehensive Metabolomics Resource Core (ERCMRC)
Southeast Center for Integrated Metabolomics (SECIM)
Resource Center for Stable Isotope-Resolved Metabolomics (RC-SIRM)
Metabolomics Core at Mayo Clinic

more about our RCMRCs


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