Summary of Study ST002252
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001440. The data can be accessed directly via it's Project DOI: 10.21228/M8KQ6P This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002252 |
Study Title | Lipidomics analysis on Arabidopsis autophagy mutants |
Study Summary | Autophagy is an essential cellular process in eukaryotes that degrades and recycles macromolecules and organelles. Defects in autophagy is known to affect metabolism, including the lipidome. Genetic approaches have identified a series of AuTophaGy-related (ATG) genes in Arabidopsis. In this study we used WT (ecotype Col-0) and two Arabidopsis autophagy-defective mutants, atg7 and atg9 to perform a multi-omics study on the effect of nitrogen starvation treatment, which induces autophagy. Specifically, we have quantified ~100 lipids from leaf and root tissues of WT, atg7 and atg9 mutant plants, under either autophagy-inducing conditions (-N) or normal nitrogen conditions (+N). The lipid species we quantified include: DGDG, MGDG, LPC, LPE, PE, LPG, PC, PA, PG, PI, and PS. Our study sheds lights on the understanding of the relationships between autophagy and metabolism, especially lipid metabolism. |
Institute | Iowa State University |
Department | Biochemistry Biophysics, and Molecular Biology |
Laboratory | Nikolau Lab |
Last Name | Ding |
First Name | Geng |
Address | 2252 Molecular Biology BLDG, Pammel Drive |
gengding@iastate.edu | |
Phone | 515-294-0347 |
Submit Date | 2022-02-21 |
Raw Data Available | Yes |
Raw Data File Type(s) | mzML |
Analysis Type Detail | MS(Dir. Inf.) |
Release Date | 2023-02-21 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Plant; Subject species: Arabidopsis thaliana (Factor headings shown in green)
mb_sample_id | local_sample_id | Expeimental factors |
---|---|---|
SA216939 | sample72 | atg7-2 -N Leaf |
SA216940 | sample60 | atg7-2 -N Leaf |
SA216941 | sample84 | atg7-2 -N Leaf |
SA216942 | sample36 | atg7-2 -N Leaf |
SA216931 | sample34 | atg7-2 +N Leaf |
SA216932 | sample58 | atg7-2 +N Leaf |
SA216933 | sample70 | atg7-2 +N Leaf |
SA216934 | sample82 | atg7-2 +N Leaf |
SA216943 | sample83 | atg7-2 -N Root |
SA216944 | sample59 | atg7-2 -N Root |
SA216945 | sample35 | atg7-2 -N Root |
SA216946 | sample71 | atg7-2 -N Root |
SA216935 | sample69 | atg7-2 +N Root |
SA216936 | sample57 | atg7-2 +N Root |
SA216937 | sample33 | atg7-2 +N Root |
SA216938 | sample81 | atg7-2 +N Root |
SA216953 | sample32 | atg9-4 -N Leaf |
SA216954 | sample80 | atg9-4 -N Leaf |
SA216955 | sample56 | atg9-4 -N Leaf |
SA216947 | sample54 | atg9-4 +N Leaf |
SA216948 | sample78 | atg9-4 +N Leaf |
SA216949 | sample30 | atg9-4 +N Leaf |
SA216956 | sample55 | atg9-4 -N Root |
SA216957 | sample31 | atg9-4 -N Root |
SA216958 | sample79 | atg9-4 -N Root |
SA216950 | sample53 | atg9-4 +N Root |
SA216951 | sample29 | atg9-4 +N Root |
SA216952 | sample77 | atg9-4 +N Root |
SA216909 | QC11 | Quality control samples |
SA216910 | QC07 | Quality control samples |
SA216911 | QC09 | Quality control samples |
SA216912 | QC08 | Quality control samples |
SA216913 | QC06 | Quality control samples |
SA216914 | QC10 | Quality control samples |
SA216923 | sample76 | WT -N Leaf |
SA216924 | sample64 | WT -N Leaf |
SA216925 | sample52 | WT -N Leaf |
SA216926 | sample28 | WT -N Leaf |
SA216915 | sample50 | WT +N Leaf |
SA216916 | sample62 | WT +N Leaf |
SA216917 | sample26 | WT +N Leaf |
SA216918 | sample74 | WT +N Leaf |
SA216927 | sample27 | WT -N Root |
SA216928 | sample63 | WT -N Root |
SA216929 | sample75 | WT -N Root |
SA216930 | sample51 | WT -N Root |
SA216919 | sample49 | WT +N Root |
SA216920 | sample25 | WT +N Root |
SA216921 | sample61 | WT +N Root |
SA216922 | sample73 | WT +N Root |
Showing results 1 to 50 of 50 |