Summary of Study ST002212

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001413. The data can be accessed directly via it's Project DOI: 10.21228/M82X3Z This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002212
Study TitleHuman fecal metabolome profiles under 3 different dietary terms
Study SummaryThe gut microbiota produce numerous metabolites that affect host physiology, although the effects of the daily diet on human intestinal metabolome profiles and robustness are not well understood. Here we investigated the robustness of the human intestinal environment through gut microbiome and metabolome profiles in response to daily dietary fluctuations. We analyzed 176 fecal samples from 25 healthy Japanese individuals under three dietary conditions, including heterogeneous and homogeneous diets. Human intestinal metabolome and microbiome profiles were unique to each individual and were robust under daily dietary fluctuation in most cases. Our findings provide insight into the use of intestinal environment information for clinical studies.
Institute
Keio University
DepartmentInstitute for Advanced Biosciences
Last NameFukuda
First NameShinji
AddressKakuganji 246-2, Mizukami, Tsuruoka City Yamagata,Japan
Emailsfukuda@sfc.keio.ac.jp
Phone+81-235-29-800
Submit Date2022-06-29
Raw Data AvailableYes
Raw Data File Type(s)OTHER
Analysis Type DetailLC-MS
Release Date2023-07-28
Release Version1
Shinji Fukuda Shinji Fukuda
https://dx.doi.org/10.21228/M82X3Z
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Combined analysis:

Analysis ID AN003616 AN003617
Analysis type MS MS
Chromatography type CE CE
Chromatography system Agilent CE Agilent CE
Column Fused-silica,50um(cation) COSMO(+),50um(anion
MS Type ESI ESI
MS instrument type Other Other
MS instrument name Agilent CE-TOFMS Agilent CE-TOFMS
Ion Mode POSITIVE NEGATIVE
Units μmol/g μmol/g
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