Summary of Study ST001993
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001266. The data can be accessed directly via it's Project DOI: 10.21228/M82M5M This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST001993 |
Study Title | CE-MS based metabolomics to study plasma samples that reveal new pathways implicated in SARS-CoV-2 pathogenesis |
Study Summary | CE-MS based metabolomics was used in this study to analize COVID-19 disease and the susceptibility to SARS-CoV-2. In total, 63 plasma samples were analyzed and different comparisons were performed. To our knowledge, CE-MS has never been used to study COVID-19 and it is considered in this study an appropriate approach to extend the polar metabolome beyond what has been obtained by LC-MS and GC-MS |
Institute | Universidad CEU San Pablo |
Department | Pharmacy |
Laboratory | Centro de Metabolomica y Bioanálisis (CEMBIO) |
Last Name | Barbas |
First Name | Coral |
Address | CEU Universities, Urbanización Montepríncipe |
cbarbas@ceu.es | |
Phone | +34 913724700 |
Submit Date | 2021-11-16 |
Raw Data Available | Yes |
Raw Data File Type(s) | d |
Analysis Type Detail | LC-MS |
Release Date | 2021-12-05 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
Analysis ID | AN003250 |
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Analysis type | MS |
Chromatography type | Unspecified |
Chromatography system | 7100 capillary electrophoresis (CE) |
Column | fused-silica capillary from Agilent Technologies (total length,100 cm; inner diameter,50um) |
MS Type | ESI |
MS instrument type | Other |
MS instrument name | Agilent 6230 TOF |
Ion Mode | POSITIVE |
Units | Peak Area |
Chromatography:
Chromatography ID: | CH002395 |
Chromatography Summary: | Metabolite separation was carried out using a previously developed method in a fused-silica capillary from Agilent Technologies (total length, 100 cm; inner diameter, 50 µm) 1. Before each analysis, the capillary was flushed with background electrolyte (BGE) (1 M formic acid in 10% MeOH) for 5 min at 950 mbar. Samples were injected over 50 s at 50 mbar, and to improve the analysis reproducibility, BGE was injected for 10 s at 100 mbar after each sample injection. The separation was performed with an internal pressure of 25 mbar and 30 kV voltage, and the current observed under these conditions was 30 µA. The total analytical run time was 35 min. |
Instrument Name: | 7100 capillary electrophoresis (CE) |
Column Name: | fused-silica capillary from Agilent Technologies (total length,100 cm; inner diameter,50um) |
Chromatography Type: | Unspecified |