Summary of Study ST001905

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001200. The data can be accessed directly via it's Project DOI: 10.21228/M8KX3M This work is supported by NIH grant, U2C- DK119886.


Perform statistical analysis  |  Show all samples  |  Show named metabolites  |  Download named metabolite data  
Download mwTab file (text)   |  Download mwTab file(JSON)
Study IDST001905
Study TitleMetabolomic profiling of saliva in diabetes patients
Study SummaryWe performed comprehensive profiling of plasma and salivary metabolomes, and investigated multivariate covariations with clinical markers of oral and cardiometabolic health in healthy subjects and type 2 diabetes patients. The key findings highlight the potential utility of salivary metabolites for reflecting cardiometabolic changes, including hyperglycemia and dyslipidemia. Our study shows that analysis of panels of salivary metabolites may become an attractive alternative to blood testing for screening of metabolic disorders.
Osaka University
Last NameSakanaka
First NameAkito
Address1-8 Yamadaoka, Suita, Osaka 565-0871, Japan
Submit Date2021-08-15
Analysis Type DetailGC-MS
Release Date2022-12-09
Release Version1
Akito Sakanaka Akito Sakanaka application/zip

Select appropriate tab below to view additional metadata details:


Collection ID:CO001976
Collection Summary:Four calibrated and licensed dentists performed oral examinations, and saliva collection the same day as blood collection. All subjects were asked to refrain from eating, drinking, or brushing for at least 1 h prior to undergoing these procedures. The subject was asked to expectorate unstimulated whole saliva over a 10-min period into a 50-mL tube (Corning, Corning, NY, USA) kept on ice. Following incubation on ice for 15 min, the aqueous layer of each sample was pipetted off, and samples with volumes of at least 1 and 0.1 mL were aliquoted into 2-mL tubes kept at 4℃ in a CubeCooler® as study and quality control (QC) samples, respectively. Subsequently, they were frozen with liquid nitrogen and stored at −80℃ until analysis.
Sample Type:Saliva