Summary of Study ST000646

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000460. The data can be accessed directly via it's Project DOI: 10.21228/M8M027 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

Perform statistical analysis  |  Show all samples  |  Show named metabolites  |  Download named metabolite data  
Download mwTab file (text)   |  Download mwTab file(JSON)
Study IDST000646
Study TitleEffects of Exercise on Dystrophic Mouse Muscle TCA Cycle (part II)
Study SummaryWe will use male C57BL10, mdx, and nNOS-/- mice (n = 10 each group) to characterize the skeletal and cardiac muscle metabolomes. Half of the mice in each group will remain sedentary while the other half will be subjected to a single bout of treadmill exercise to exhaustion. Mice will be euthanized immediately postexercise and blood, hearts, and hindlimb muscles will be harvested and frozen as detailed in the General Methods. The heart and gastrocnemius, soleus, and quadriceps muscles of one hindlimb will be sent to the Mayo Clinic Metabolomics Resource Core. The heart and quadriceps muscle will be used for untargeted metabolomics profiling (LC/MS) while the gastrocnemius and soleus muscles will be used for targeted analyses of amino acids plus amino metabolites, non-esterified fatty acids, and citric acid cycle intermediates.
Institute
Mayo Clinic
Last NameThomas
First NameGail
AddressPenn State Hershey Heart and Vascular Institute Penn State College of Medicine 500 University Drive, MC H047 Hershey, PA 17033
Emailgthomas4@hmc.psu.edu
Phone717-531-0003, ext. 287087
Submit Date2017-06-23
Analysis Type DetailGC-MS
Release Date2019-07-17
Release Version1
Gail Thomas Gail Thomas
https://dx.doi.org/10.21228/M8M027
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mouse; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Time point Grouping
SA036469Sample # 7Post Run RUN-BL10 Control
SA036470Sample # 9Post Run RUN-BL10 Control
SA036471Sample # 10Post Run RUN-BL10 Control
SA036472Sample # 6Post Run RUN-BL10 Control
SA036473Sample # 8Post Run RUN-BL10 Control
SA036474Sample # 28Post Run RUN-MDX
SA036475Sample # 26Post Run RUN-MDX
SA036476Sample # 30Post Run RUN-MDX
SA036477Sample # 27Post Run RUN-MDX
SA036478Sample # 29Post Run RUN-MDX
SA036479Sample # 18Post Run RUN-nNOS-/-
SA036480Sample # 19Post Run RUN-nNOS-/-
SA036481Sample # 20Post Run RUN-nNOS-/-
SA036482Sample # 17Post Run RUN-nNOS-/-
SA036483Sample # 16Post Run RUN-nNOS-/-
SA036484Sample # 5Sedentary SED-BL10 Control
SA036485Sample # 4Sedentary SED-BL10 Control
SA036486Sample # 3Sedentary SED-BL10 Control
SA036487Sample # 1Sedentary SED-BL10 Control
SA036488Sample # 2Sedentary SED-BL10 Control
SA036489Sample # 25Sedentary SED-MDX
SA036490Sample # 24Sedentary SED-MDX
SA036491Sample # 21Sedentary SED-MDX
SA036492Sample # 22Sedentary SED-MDX
SA036493Sample # 23Sedentary SED-MDX
SA036494Sample # 15Sedentary SED-nNOS-/-
SA036495Sample # 14Sedentary SED-nNOS-/-
SA036496Sample # 11Sedentary SED-nNOS-/-
SA036497Sample # 12Sedentary SED-nNOS-/-
SA036498Sample # 13Sedentary SED-nNOS-/-
Showing results 1 to 30 of 30
  logo