Summary of Study ST001973

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001253. The data can be accessed directly via it's Project DOI: 10.21228/M8R98V This work is supported by NIH grant, U2C- DK119886.

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Study IDST001973
Study TitleAnalytical methodology for a metabolome atlas of goat’s plasma, milk and feces using 1H-NMR and UHPLC-HRMS:MS/feces
Study SummaryMetabolomics has been increasingly used in animal and food sciences. Animal health is one of the most important factors that can also alter animal integrity and welfare. Some studies have already investigated the link between health and metabolic profile of dairy animals. These studies in metabolomics often consider a single type of sample using a single analytical platform (Nuclear Magnetic Resonance or Mass Spectrometry). Only few studies with multi-platform approaches are also used with a single or a multi type of sample, but they mainly consider dairy cows metabolome although dairy goats present similar diseases, that it could be interesting to detect early to preserve animal health and milk production. This study aims to create a metabolic atlas of goat plasma, milk, and feces, based on healthy animals. Our study describes a Standard Operating Procedure for three goat matrices: blood plasma, milk, and feces using multiple platforms (NMR (1H), UHPLC (RP)-MS and UHPLC (HILIC)-MS) that follows a unique sample preparation procedure for each sample type to be analyzed on multi-platforms basis. Our method was evaluated for its robustness and allowed a better characterization of goat metabolic profile in healthy conditions.
Institute
INSERM
DepartmentINSERM
Last NameMartias
First NameCecile
Address10 Boulevard tonnelé, Indre et Loire, 37000, France
Emailcecile.martias@univ-tours.fr
Phone0247366351
Submit Date2021-09-26
Analysis Type DetailLC-MS
Release Date2022-01-02
Release Version1
Cecile Martias Cecile Martias
https://dx.doi.org/10.21228/M8R98V
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Mammal; Subject species: Capra hircus (Factor headings shown in green)

mb_sample_id local_sample_id Protcole
SA185204Phenomet_C18_POS_F-P1-N8P1
SA185205Phenomet_C18_POS_F-P1-N9P1
SA185206Phenomet_C18_POS_F-P1-N6P1
SA185207Phenomet_C18_POS_F-P1-N1P1
SA185208Phenomet_C18_POS_F-P1-N7P1
SA185209Phenomet_C18_POS_F-P1-N5P1
SA185210Phenomet_C18_POS_F-P1-N10P1
SA185211Phenomet_C18_POS_F-P1-N3P1
SA185212Phenomet_C18_POS_F-P1-N2P1
SA185213Phenomet_C18_POS_F-P1-N4P1
SA185214Phenomet_C18_POS_F-P2-N7P2
SA185215Phenomet_C18_POS_F-P2-N8P2
SA185216Phenomet_C18_POS_F-P2-N6P2
SA185217Phenomet_C18_POS_F-P2-N9P2
SA185218Phenomet_C18_POS_F-P2-N2P2
SA185219Phenomet_C18_POS_F-P2-N5P2
SA185220Phenomet_C18_POS_F-P2-N10P2
SA185221Phenomet_C18_POS_F-P2-N1P2
SA185222Phenomet_C18_POS_F-P2-N3P2
SA185223Phenomet_C18_POS_F-P2-N4P2
SA185224Phenomet_C18_POS_F-P4-N6P4
SA185225Phenomet_C18_POS_F-P4-N7P4
SA185226Phenomet_C18_POS_F-P4-N9P4
SA185227Phenomet_C18_POS_F-P4-N8P4
SA185228Phenomet_C18_POS_F-P4-N5P4
SA185229Phenomet_C18_POS_F-P4-N4P4
SA185230Phenomet_C18_POS_F-P4-N10P4
SA185231Phenomet_C18_POS_F-P4-N1P4
SA185232Phenomet_C18_POS_F-P4-N3P4
SA185233Phenomet_C18_POS_F-P4-N2P4
SA185234Phenomet_C18_POS_F-P5-N6P5
SA185235Phenomet_C18_POS_F-P5-N7P5
SA185236Phenomet_C18_POS_F-P5-N9P5
SA185237Phenomet_C18_POS_F-P5-N5P5
SA185238Phenomet_C18_POS_F-P5-N8P5
SA185239Phenomet_C18_POS_F-P5-N4P5
SA185240Phenomet_C18_POS_F-P5-N10P5
SA185241Phenomet_C18_POS_F-P5-N1P5
SA185242Phenomet_C18_POS_F-P5-N3P5
SA185243Phenomet_C18_POS_F-P5-N2P5
SA185244Phenomet_C18_POS_F-P6-N7P6
SA185245Phenomet_C18_POS_F-P6-N9P6
SA185246Phenomet_C18_POS_F-P6-N6P6
SA185247Phenomet_C18_POS_F-P6-N8P6
SA185248Phenomet_C18_POS_F-P6-N3P6
SA185249Phenomet_C18_POS_F-P6-N1P6
SA185250Phenomet_C18_POS_F-P6-N10P6
SA185251Phenomet_C18_POS_F-P6-N2P6
SA185252Phenomet_C18_POS_F-P6-N4P6
SA185253Phenomet_C18_POS_F-P6-N5P6
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