Summary of Study ST002472

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001596. The data can be accessed directly via it's Project DOI: 10.21228/M8D701 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002472
Study TitleLinking bacterial metabolites to disease-associated microbes to uncover mechanisms of host-microbial interactions in intestinal inflammation. Veillonella parvula cell and media profiling
Study SummaryUnderstanding the role of the gut microbiome in inflammatory and autoimmune diseases requires the identification of microbial molecular effectors and their link to host pathophysiology. Here, we present a framework to identify and characterize novel microbial metabolites in patient samples and to directly link their production to disease-associated microbes. We applied this approach to investigate the spectrum of disease severity and treatment response in ulcerative colitis (UC) using longitudinal metabolite and strain profiles combined with paired plasma profiles.
Institute
Broad Institute of MIT and Harvard
Last NameXavier
First NameRamnik
Address415 Main Street
Emailrxavier@broadinstitute.org
Phone617717084
Submit Date2023-02-10
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2024-02-12
Release Version1
Ramnik Xavier Ramnik Xavier
https://dx.doi.org/10.21228/M8D701
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Bacteria; Subject species: Veillonella parvula (Factor headings shown in green)

mb_sample_id local_sample_id Matrix Sample Type Tretment
SA247708C_40Cell_pool QC_Titration -
SA247709C_80Cell_pool QC_Titration -
SA247710C_100Cell_pool QC_Titration -
SA247711C_20Cell_pool QC_Titration -
SA247712C_60Cell_pool QC_Titration -
SA247699L_C1Cell Experiment Lactate
SA247700L_C3Cell Experiment Lactate
SA247701L_C2Cell Experiment Lactate
SA247702LN_C3Cell Experiment Lactate+Nitrate
SA247703LN_C2Cell Experiment Lactate+Nitrate
SA247704LN_C1Cell Experiment Lactate+Nitrate
SA247705N_C2Cell Experiment Nitrate
SA247706N_C3Cell Experiment Nitrate
SA247707N_C1Cell Experiment Nitrate
SA247713SM_80Media_pool QC_Titration -
SA247714SM_40Media_pool QC_Titration -
SA247715SM_20Media_pool QC_Titration -
SA247716SM_60Media_pool QC_Titration -
SA247717SM_100Media_pool QC_Titration -
SA247718L_SM1Spent Media Experiment Lactate
SA247719L_SM2Spent Media Experiment Lactate
SA247720L_SM3Spent Media Experiment Lactate
SA247721LN_SM1Spent Media Experiment Lactate+Nitrate
SA247722LN_SM3Spent Media Experiment Lactate+Nitrate
SA247723LN_SM2Spent Media Experiment Lactate+Nitrate
SA247724N_SM3Spent Media Experiment Nitrate
SA247725N_SM1Spent Media Experiment Nitrate
SA247726N_SM2Spent Media Experiment Nitrate
SA247727L_UM1Unspent Media Experiment Lactate
SA247728L_UM3Unspent Media Experiment Lactate
SA247729L_UM2Unspent Media Experiment Lactate
SA247730LN_UM3Unspent Media Experiment Lactate+Nitrate
SA247731LN_UM1Unspent Media Experiment Lactate+Nitrate
SA247732LN_UM2Unspent Media Experiment Lactate+Nitrate
SA247733N_UM3Unspent Media Experiment Nitrate
SA247734N_UM2Unspent Media Experiment Nitrate
SA247735N_UM1Unspent Media Experiment Nitrate
Showing results 1 to 37 of 37
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