Summary of Study ST002919

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001814. The data can be accessed directly via it's Project DOI: 10.21228/M87D9M This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002919
Study TitleShort-term metabolic insulin response of DINCH- and MINCH-treated cells
Study SummaryIn the second part of the project, we examined the short-term metabolic insulin response of DINAH- and MINCH-treated cells and compared them with rosiglitazone-differentiated cells. For this purpose, the human SGBS preadipocyte cell line was exposed to differentiation media conditioned with DINCH (10 nM or 10 µM), MINCH (10 nM or 10 µM), or rosiglitazone, and the insulin response was measured by analyzing the changes in glycolysis and PPP between insulin-stimulated and non-insulin-stimulated cells. In conclusion, the insulin response of glycolysis and PPP of cells treated with 10 µM MINCH, but not with 10 nM MINCH or DINCH, was similar to cells differentiated with rosiglitazone.
Institute
Helmholtz Centre for Environmental Research
Last NameEngelmann
First NameBeatrice
AddressPermoserstr. 15
Emailbeatrice.engelmann@ufz.de
Phone00493412351099
Submit Date2023-10-08
Raw Data AvailableYes
Raw Data File Type(s)wiff
Analysis Type DetailLC-MS
Release Date2023-11-01
Release Version1
Beatrice Engelmann Beatrice Engelmann
https://dx.doi.org/10.21228/M87D9M
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Cultured cells; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Treatment Replicate
SA316808MINCH_High_-_1DINCH 10µM minus Insulin 1
SA316809DINCH_High_-_1DINCH 10µM minus Insulin 1
SA316810DINCH_High_-_2DINCH 10µM minus Insulin 2
SA316811MINCH_High_-_2DINCH 10µM minus Insulin 2
SA316812MINCH_High_-_3DINCH 10µM minus Insulin 3
SA316813DINCH_High_-_3DINCH 10µM minus Insulin 3
SA316814MINCH_High_-_4DINCH 10µM minus Insulin 4
SA316815DINCH_High_-_4DINCH 10µM minus Insulin 4
SA316816MINCH_High_-_5DINCH 10µM minus Insulin 5
SA316817DINCH_High_-_5DINCH 10µM minus Insulin 5
SA316798MINCH_High_SN_-_1DINCH 10µM minus Insulin supernatant 1
SA316799DINCH_High_SN_-_1DINCH 10µM minus Insulin supernatant 1
SA316800DINCH_High_SN_-_2DINCH 10µM minus Insulin supernatant 2
SA316801MINCH_High_SN_-_2DINCH 10µM minus Insulin supernatant 2
SA316802DINCH_High_SN_-_3DINCH 10µM minus Insulin supernatant 3
SA316803MINCH_High_SN_-_3DINCH 10µM minus Insulin supernatant 3
SA316804DINCH_High_SN_-_4DINCH 10µM minus Insulin supernatant 4
SA316805MINCH_High_SN_-_4DINCH 10µM minus Insulin supernatant 4
SA316806DINCH_High_SN_-_5DINCH 10µM minus Insulin supernatant 5
SA316807MINCH_High_SN_-_5DINCH 10µM minus Insulin supernatant 5
SA316828DINCH_High_+_1DINCH 10µM plus Insulin 1
SA316829MINCH_High_+_1DINCH 10µM plus Insulin 1
SA316830DINCH_High_+_2DINCH 10µM plus Insulin 2
SA316831MINCH_High_+_2DINCH 10µM plus Insulin 2
SA316832MINCH_High_+_3DINCH 10µM plus Insulin 3
SA316833DINCH_High_+_3DINCH 10µM plus Insulin 3
SA316834MINCH_High_+_4DINCH 10µM plus Insulin 4
SA316835DINCH_High_+_4DINCH 10µM plus Insulin 4
SA316836DINCH_High_+_5DINCH 10µM plus Insulin 5
SA316837MINCH_High_+_5DINCH 10µM plus Insulin 5
SA316818MINCH_High_SN_+_1DINCH 10µM plus Insulin supernatant 1
SA316819DINCH_High_SN_+_1DINCH 10µM plus Insulin supernatant 1
SA316820MINCH_High_SN_+_2DINCH 10µM plus Insulin supernatant 2
SA316821DINCH_High_SN_+_2DINCH 10µM plus Insulin supernatant 2
SA316822MINCH_High_SN_+_3DINCH 10µM plus Insulin supernatant 3
SA316823DINCH_High_SN_+_3DINCH 10µM plus Insulin supernatant 3
SA316824MINCH_High_SN_+_4DINCH 10µM plus Insulin supernatant 4
SA316825DINCH_High_SN_+_4DINCH 10µM plus Insulin supernatant 4
SA316826DINCH_High_SN_+_5DINCH 10µM plus Insulin supernatant 5
SA316827MINCH_High_SN_+_5DINCH 10µM plus Insulin supernatant 5
SA316768DINCH_Low_-_1DINCH 10nM minus Insulin 1
SA316769MINCH_Low_-_1DINCH 10nM minus Insulin 1
SA316770MINCH_Low_-_2DINCH 10nM minus Insulin 2
SA316771DINCH_Low_-_2DINCH 10nM minus Insulin 2
SA316772MINCH_Low_-_3DINCH 10nM minus Insulin 3
SA316773DINCH_Low_-_3DINCH 10nM minus Insulin 3
SA316774MINCH_Low_-_4DINCH 10nM minus Insulin 4
SA316775DINCH_Low_-_4DINCH 10nM minus Insulin 4
SA316776MINCH_Low_-_5DINCH 10nM minus Insulin 5
SA316777DINCH_Low_-_5DINCH 10nM minus Insulin 5
SA316758DINCH_Low_SN_-_1DINCH 10nM minus Insulin supernatant 1
SA316759MINCH_Low_SN_-_1DINCH 10nM minus Insulin supernatant 1
SA316760DINCH_Low_SN_-_2DINCH 10nM minus Insulin supernatant 2
SA316761MINCH_Low_SN_-_2DINCH 10nM minus Insulin supernatant 2
SA316762DINCH_Low_SN_-_3DINCH 10nM minus Insulin supernatant 3
SA316763MINCH_Low_SN_-_3DINCH 10nM minus Insulin supernatant 3
SA316764DINCH_Low_SN_-_4DINCH 10nM minus Insulin supernatant 4
SA316765MINCH_Low_SN_-_4DINCH 10nM minus Insulin supernatant 4
SA316766MINCH_Low_SN_-_5DINCH 10nM minus Insulin supernatant 5
SA316767DINCH_Low_SN_-_5DINCH 10nM minus Insulin supernatant 5
SA316788MINCH_Low_+_1DINCH 10nM plus Insulin 1
SA316789DINCH_Low_+_1DINCH 10nM plus Insulin 1
SA316790DINCH_Low_+_2DINCH 10nM plus Insulin 2
SA316791MINCH_Low_+_2DINCH 10nM plus Insulin 2
SA316792DINCH_Low_+_3DINCH 10nM plus Insulin 3
SA316793MINCH_Low_+_3DINCH 10nM plus Insulin 3
SA316794DINCH_Low_+_4DINCH 10nM plus Insulin 4
SA316795MINCH_Low_+_4DINCH 10nM plus Insulin 4
SA316796MINCH_Low_+_5DINCH 10nM plus Insulin 5
SA316797DINCH_Low_+_5DINCH 10nM plus Insulin 5
SA316778DINCH_Low_SN_+_1DINCH 10nM plus Insulin supernatant 1
SA316779MINCH_Low_SN_+_1DINCH 10nM plus Insulin supernatant 1
SA316780DINCH_Low_SN_+_2DINCH 10nM plus Insulin supernatant 2
SA316781MINCH_Low_SN_+_2DINCH 10nM plus Insulin supernatant 2
SA316782MINCH_Low_SN_+_3DINCH 10nM plus Insulin supernatant 3
SA316783DINCH_Low_SN_+_3DINCH 10nM plus Insulin supernatant 3
SA316784DINCH_Low_SN_+_4DINCH 10nM plus Insulin supernatant 4
SA316785MINCH_Low_SN_+_4DINCH 10nM plus Insulin supernatant 4
SA316786MINCH_Low_SN_+_5DINCH 10nM plus Insulin supernatant 5
SA316787DINCH_Low_SN_+_5DINCH 10nM plus Insulin supernatant 5
SA316843Rosi_-_1Rosiglitazone minus insulin 1
SA316844Rosi_-_2Rosiglitazone minus insulin 2
SA316845Rosi_-_3Rosiglitazone minus insulin 3
SA316846Rosi_-_4Rosiglitazone minus insulin 4
SA316847Rosi_-_5Rosiglitazone minus insulin 5
SA316838Rosi_SN_-_1Rosiglitazone minus insulin supernatant 1
SA316839Rosi_SN_-_2Rosiglitazone minus insulin supernatant 2
SA316840Rosi_SN_-_3Rosiglitazone minus insulin supernatant 3
SA316841Rosi_SN_-_4Rosiglitazone minus insulin supernatant 4
SA316842Rosi_SN_-_5Rosiglitazone minus insulin supernatant 5
SA316853Rosi_+_1Rosiglitazone plus insulin 1
SA316854Rosi_+_2Rosiglitazone plus insulin 2
SA316855Rosi_+_3Rosiglitazone plus insulin 3
SA316856Rosi_+_4Rosiglitazone plus insulin 4
SA316857Rosi_+_5Rosiglitazone plus insulin 5
SA316848Rosi_SN_+_1Rosiglitazone plus insulin supernatant 1
SA316849Rosi_SN_+_2Rosiglitazone plus insulin supernatant 2
SA316850Rosi_SN_+_3Rosiglitazone plus insulin supernatant 3
SA316851Rosi_SN_+_4Rosiglitazone plus insulin supernatant 4
SA316852Rosi_SN_+_5Rosiglitazone plus insulin supernatant 5
Showing results 1 to 100 of 100
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