Summary of Study ST003040
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001892. The data can be accessed directly via it's Project DOI: 10.21228/M8572M This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST003040 |
| Study Title | MM.1S Myeloma tumor cells and tumors made by subcutaneously injecting 1M Luc+/GFP+ MM.1S cells treated with 50 μM BMS309403 and Vehicle (PBS with a matched concentration of 5% DMSO) |
| Study Summary | MM.1S Myeloma tumor cells were treated with 50 μM BMS309403 once over 24 hours in vitro or at 5mg/kg X3 per week over 32 days in vivo. In Vivo tumors were made by subcutaneously injecting 1M Luc+/GFP+ MM.1S cells mixed with Matrigel in a 1:1 ratio into the backs of 8-week old, female SCID-Beige. Vehicle (PBS with a matched concentration of 5% DMSO) was used as control for each condition. |
| Institute | Mainehealth |
| Last Name | Reagan |
| First Name | Michaela |
| Address | 81 Research Drive, Scarborough, ME, Portland, ME, 04074, USA |
| Michaela.Reagan@mainehealth.org | |
| Phone | (207)396-8196 |
| Submit Date | 2023-12-20 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | mzXML |
| Analysis Type Detail | LC-MS |
| Release Date | 2024-03-25 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
| Analysis ID | AN004987 |
|---|---|
| Analysis type | MS |
| Chromatography type | None (Direct infusion) |
| Chromatography system | none |
| Column | none |
| MS Type | ESI |
| MS instrument type | QTRAP |
| MS instrument name | AB Sciex 4000 QTrap |
| Ion Mode | UNSPECIFIED |
| Units | Corrected Peak intensities |
MS:
| MS ID: | MS004727 |
| Analysis ID: | AN004987 |
| Instrument Name: | AB Sciex 4000 QTrap |
| Instrument Type: | QTRAP |
| MS Type: | ESI |
| MS Comments: | The analysis was made in POSITIVE and NEGATIVE polarities. Extract MS/MS data: Fragments_POS= Mass tolerance (Da) 0.3, Fragments_NEG= Mass tolerance (Da) 0.5 spectrum peak. Source parameters: GS1=15, GS2=20, CUR= 10, ISV=5300, T=150. Lipids were analyzed in multiple precursor ion scattering (MPIS). Identification of Lipids was using LipidView 1.3 beta (Sciex) and exported to MarkerView 1.4 in a view mode: Corrected intensities (normalization with the high peak intensity) |
| Ion Mode: | UNSPECIFIED |
