Summary of Study ST000050
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000048. The data can be accessed directly via it's Project DOI: 10.21228/M8101K This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST000050 |
Study Title | Preterm Neonatal Urinary Renal Developmental and acute kidney injury Metabolomic Profiling |
Study Type | Metabolomics |
Study Summary | Brophy and Askenazi hypothesize that postnatal renal maturation results in specific identifiable patterns of urinary metabolites and that these profiles will be altered in the presence of AKI. Their long-term goal is to identify novel metabolomics urinary profiles that can provide real-time evidence of evolving neonatal renal injury thereby allowing earlier diagnosis and treatment.This study includes 40 pre-term infants age 2 days. Twenty infants were identified as not having AKI (11 females, mean gestational age=182.8 days, mean birth weight=834.0 grams) and 20 infants were identified as having AKI (13 females, mean gestational age=183.9 days, mean birth weight=815.8 grams). There are no statistical differences between the two groups based on gender, gestational age, and birth weight. |
Institute | University of North Carolina |
Department | RTI RCMRC |
Laboratory | Sumner Lab |
Last Name | Sumner |
First Name | Susan |
Address | Eastern Regional Comprehensive Metabolomics Resource Core, UNC Nutrition Research Institute, 500 Laureate Way, Kannapolis, NC, 28081 |
susan_sumner @unc.edu | |
Phone | 704-250-5066 |
Submit Date | 2014-04-30 |
Num Groups | 2 |
Total Subjects | 40 |
Raw Data Available | Yes |
Raw Data File Type(s) | fid |
Uploaded File Size | 28 M |
Analysis Type Detail | NMR |
Release Date | 2018-08-27 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
NMR:
NMR ID: | NM000023 |
Analysis ID: | AN000086 |
Instrument Name: | Bruker Avance III |
Instrument Type: | FT-NMR |
NMR Experiment Type: | 1D 1H |
Field Frequency Lock: | Deuterium |
Standard Concentration: | 0.5mM |
Spectrometer Frequency: | 950 MHz |
NMR Probe: | cyrogenically cooled ATMA inverse probe |
NMR Solvent: | D2O |
NMR Tube Size: | 3mm |
Shimming Method: | Gradient |
Pulse Sequence: | NOESYpr1d |
Water Suppression: | yes |
Pulse Width: | 19.9298 |
Receiver Gain: | 4 |
Offset Frequency: | 4468.3 |
Chemical Shift Ref Cpd: | formate |
Temperature: | 25 degrees celsius |
Number Of Scans: | 64 |
Dummy Scans: | 4 |
Acquisition Time: | 1.73 seconds |
Spectral Width: | 19.9298 |
Num Data Points Acquired: | 65536 |
Real Data Points: | 65536 |
Line Broadening: | 0.5 |
Zero Filling: | yes |
Apodization: | Lorentzian |
Baseline Correction Method: | quad |