Summary of Study ST001981

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001257. The data can be accessed directly via it's Project DOI: 10.21228/M87986 This work is supported by NIH grant, U2C- DK119886.

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Study IDST001981
Study TitleNon-destructive characterization of Mesenchymal stem cells
Study SummaryCulture media from the growth of three different MSC cell lines (two bone marrow, one iPSC) were sampled daily for NMR metabolomics analysis. T cell proliferation and IDO assays were used as surrogates of anti-inflammatory function. Linear regression was used to assess the media metabolic changes over time, and partial least squares regression (PLSR) was then used to obtain predictive media markers (PMMs) based on variable importance in projection (VIP) scores. In addition, pathway analysis was performed to show the relations between media metabolites (MMs) and cell metabolites (CMs).
Institute
University of Georgia
Last NameShen
First NameXunan
Address315 riverbend road
Emailxs41379@uga.edu
Phone7858407009
Submit Date2021-09-16
Raw Data AvailableYes
Analysis Type DetailNMR
Release Date2021-12-01
Release Version1
Xunan Shen Xunan Shen
https://dx.doi.org/10.21228/M87986
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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NMR:

NMR ID:NM000222
Analysis ID:AN003231
Instrument Name:bruker800
Instrument Type:FT-NMR
NMR Experiment Type:1D-1H
Spectrometer Frequency:800
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