Summary of Study ST000249
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000201. The data can be accessed directly via it's Project DOI: 10.21228/M8DK5C This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST000249 |
| Study Title | Measurement of free amino acid (AA) in response to MYC |
| Study Type | treatment |
| Study Summary | The proposed study will provide us information how the different AAs are affected by MYC. MYC is known to cause increased levels of glutamin due to import and synthesis, but we hypothesize that the overall pool of free AA in the cells is reduced, especially when cells are starved. |
| Institute | University of Florida |
| Department | SECIM |
| Last Name | Schaub |
| First Name | Franz |
| Franz.Schaub@moffitt.org | |
| Submit Date | 2015-09-22 |
| Num Groups | 2 |
| Total Subjects | 6 |
| Raw Data Available | No |
| Raw Data File Type(s) | d |
| Analysis Type Detail | LC-MS |
| Release Date | 2016-09-23 |
| Release Version | 1 |
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Project:
| Project ID: | PR000201 |
| Project DOI: | doi: 10.21228/M8DK5C |
| Project Title: | Myc-directed suppression of autophagy provides therapeutic vulnerabilities targeting amino acid homeostasis |
| Project Type: | Targeted LCMS Metabolomics |
| Project Summary: | Hypothesis:MYC is suppressing the autophagy pathway which leads to impaired recycling of proteins and reduced free AA in the cells. |
| Institute: | Moffitt Cancer Center |
| Department: | Tumor Biology |
| Laboratory: | John Cleveland |
| Last Name: | Cleveland |
| First Name: | John |
| Address: | 12902 Magnolia Dr,Tampa, FL 33612 |
| Phone: | 813 745 3888 |
| Funding Source: | NIH |
