Summary of Study ST001780

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001133. The data can be accessed directly via it's Project DOI: 10.21228/M87X24 This work is supported by NIH grant, U2C- DK119886.


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Study IDST001780
Study TitleComparative analysis of metabolomic profiles in cerebrospinal fluid before and after endurance exercise
Study SummaryThis study compared the metabolomic differences in the cerebrospinal fluid of young adult volunteers between before (Pre), and 60 minutes after the 90-min run (Post).
University of California, San Diego School of Medicine
Last NameNaviaux
First NameRobert
Address214 Dickinson St., Room C-107, San Diego, CA, 92103, USA
Submit Date2021-05-03
Num Groups2
Total Subjects19
Num Males13
Num Females6
Analysis Type DetailLC-MS
Release Date2021-11-25
Release Version1
Robert Naviaux Robert Naviaux application/zip

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Project ID:PR001133
Project DOI:doi: 10.21228/M87X24
Project Title:Metabolomic changes of cerebrospinal fluid in response to endurance exercise
Project Summary:Metabolomics has emerged as a powerful new tool in precision medicine for gaining mechanistic insight into health and disease. The objective of this project was to investigate the metabolomic changes in cerebrospinal fluid (CSF) in response to endurance exercise. Young adult volunteers were enrolled, and the participants completed a monitored outdoor 90-minute run. CSF samples were collected during rest (Pre), and 60 minutes after the run (Post). Broad-spectrum targeted metabolomics was conducted using the liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). This study provided insights into the neuroprotective and mental health benefits of endurance exercise.
Institute:University of California, San Diego School of Medicine
Last Name:Naviaux
First Name:Robert
Address:214 Dickinson St., Room C-107, San Diego, CA, 92103, USA