Summary of Study ST001830

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001156. The data can be accessed directly via it's Project DOI: 10.21228/M88T3S This work is supported by NIH grant, U2C- DK119886.

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This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001830
Study TitleExhaustive analysis of endogenous oxPCs in APAP-treated mice.
Study SummaryA single dose of APAP at 300 mg/kg body weight was intraperitoneally administered into eight-week-old C57BL/6J male mice. After extraction of hepatic lipids, oxPCs were analyzed by LC/HRMS/MS. All mass spectrometry raw data obtained in this study were deposited.
Institute
Kyushu university
Last NameMatsuoka
First NameYuta
Address3-1-1 Maidashi Higashi-ku, Fukuoka, Not USCanada, 812-8582, Japan
Emailymatsu1205@gmail.com
Phone+81-92-642-6624
Submit Date2021-06-13
Raw Data AvailableYes
Raw Data File Type(s)mzML
Analysis Type DetailLC-MS
Release Date2021-10-14
Release Version1
Yuta Matsuoka Yuta Matsuoka
https://dx.doi.org/10.21228/M88T3S
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Project:

Project ID:PR001156
Project DOI:doi: 10.21228/M88T3S
Project Title:Structural Library and Visualization of Endogenously Oxidized Phosphatidylcholines Using Mass Spectrometry-based Techniques
Project Summary:Although oxidized phosphatidylcholines (oxPCs) play critical roles in numerous pathological events, the type and production site(s) of endogenous oxPCs remain unknown because of the lack of related structural information and analytical methods. Herein, a library of 465 oxPCs was constructed using high-resolution mass spectrometry (HRMS)-based analytical methods and employed to detect 70 oxPCs in mice with acetaminophen-induced acute liver failure.
Institute:Kyushu university
Last Name:Matsuoka
First Name:Yuta
Address:3-1-1 Maidashi Higashi-ku
Email:ymatsu1205@gmail.com
Phone:+81-92-642-6624
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