Summary of Study ST001611

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001036. The data can be accessed directly via it's Project DOI: 10.21228/M8SD7T This work is supported by NIH grant, U2C- DK119886.


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Study IDST001611
Study TitleMouse model of sarcoma (STS) to characterize tumor vulnerabilities and identify novel targets for anti-cancer treatment
Study SummaryFor metabolomics study, tumor-bearing mice were starved for 6 hours before sarcoma and skeletal muscles were harvested.
North Carolina State University
Last NameLiu
First NameXiaojing
AddressPolk Hall, RM 128
Submit Date2020-11-10
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2021-05-11
Release Version1
Xiaojing Liu Xiaojing Liu application/zip

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Treatment ID:TR001701
Treatment Summary:The mouse model of soft-tissue sarcoma was generated on a mixed background (129/SvJae and C57BL/6) using a combination of alleles that were previously described: Pax7CreER-T2 20, p53FL/FL 21, LSL-NrasG12D 22 and ROSA26mTmG Primary mouse soft tissue sarcomas were generated in the mouse hind limb as previously described 19 by intramuscular (IM) injection of (Z)-4-hydroxytamoxifen (4-OHT). 4-OHT was dissolved in 100% DMSO at a concentration of 10 mg/ml and 50 ul of the solution was injected into the gastrocnemius muscle.