Summary of Study ST001650
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001056. The data can be accessed directly via it's Project DOI: 10.21228/M86D8X This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001650 |
| Study Title | Changes to gut microbiota metabolism based on Clostridium difficile-induced inflammation |
| Study Summary | Determine changes to metabolites in lumen (cecal contents) of mice due to toxin production by Clostridium difficile R20291. |
| Institute | Stanford University |
| Department | Microbiology & Immunology |
| Laboratory | Sonnenburg |
| Last Name | University |
| First Name | Stanford |
| Address | 299 Campus Drive Fairchild Building Rm D315 |
| kmpruss@stanford.edu | |
| Phone | 6507212961 |
| Submit Date | 2020-12-21 |
| Num Groups | 3 |
| Total Subjects | 14 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | cdf |
| Analysis Type Detail | GC-MS |
| Release Date | 2021-01-25 |
| Release Version | 1 |
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Treatment:
| Treatment ID: | TR001740 |
| Treatment Summary: | Swiss Webster germ-free mice were tri-colonized with Bacteroides thetaiotaomicron, Clostridium sporogenes and Escherichia coli for 10 days. Mice were subsequently infected with wild-type Clostridium difficile R20291 (n=5), the isogenic toxin-deficient mutant TcdA-B-CDT- (n=5), or gavaged with PBS as an uninfected control (n=4). Cecal contents were colleged 5 days after C. difficile infection. |
