Summary of Study ST002526
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001627. The data can be accessed directly via it's Project DOI: 10.21228/M8D434 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002526 |
Study Title | Stable isotope tracing of 15N2-glutamine in orthotopic pancreatic ductal adenocarcinoma tumor bearing mice and non tumor-bearing controls |
Study Summary | Stable isotope tracing by bolus intravenous injections of 15N2-glutamine in orthotopic PDAC tumor bearing mice and non tumor-bearing controls followed by plasma sampling and tumor extraction for analysis of intratumoral metabolite labeling during the period of kinetic labeling |
Institute | University of Chicago |
Last Name | Apiz Saab |
First Name | Juan |
Address | 929 E. 57th St. |
japizsaab@uchicago.edu | |
Phone | 7738346506 |
Submit Date | 2022-08-05 |
Raw Data Available | Yes |
Raw Data File Type(s) | raw(Thermo) |
Analysis Type Detail | LC-MS |
Release Date | 2023-04-13 |
Release Version | 1 |
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Treatment:
Treatment ID: | TR002638 |
Treatment Summary: | Orthotopic tumors were implanted in C57BL6J mice at 8-12 weeks of age. 4 weeks after induction tumor-bearing mice and healthy littermate controls were treated with 15N2-glutamine (Cambridge Isotope Laboratory #NLM-1328-PK) dissolved in sterile phosphate buffered saline at 7.2mg/animal by tail vein injection as previously described (Lane et al., 2015). Briefly, animals were dosed three times at 15-minute intervals. |