MGP Database

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MGP000090

Ontology/Pathway Information

Entrez Gene ID159
Gene Nameadenylosuccinate synthase
Gene Symbol ADSS
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005886 IDA:HPACplasma membrane
GO:0004019 IDA:UniProtKBFadenylosuccinate synthase activity
GO:0005525 NAS:UniProtKBFGTP binding
GO:0000287 IEA:UniProtKB-HAMAPFmagnesium ion binding
GO:0042301 NAS:UniProtKBFphosphate ion binding
GO:0006167 IDA:UniProtKBPAMP biosynthetic process
GO:0006531 IEA:EnsemblPaspartate metabolic process
GO:0071257 IEA:EnsemblPcellular response to electrical stimulus
GO:0044208 IEA:UniProtKB-UniPathwayP'de novo' AMP biosynthetic process
GO:0006184 IEA:EnsemblPGTP catabolic process
GO:0002376 NAS:UniProtKBPimmune system process
GO:0046040 IEA:EnsemblPIMP metabolic process
GO:0055086 TAS:ReactomePnucleobase-containing small molecule metabolic process
GO:0006144 TAS:ReactomePpurine nucleobase metabolic process
GO:0009168 TAS:ReactomePpurine ribonucleoside monophosphate biosynthetic process
GO:0060359 IEA:EnsemblPresponse to ammonium ion
GO:0014074 IEA:EnsemblPresponse to purine-containing compound
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_1698Metabolism of nucleotides
REACT_522Purine metabolism
REACT_1776Purine ribonucleoside monophosphate biosynthesis
SMP Pathway Links
SMP IDDescription
SMP00535Adenine phosphoribosyltransferase deficiency (APRT)
SMP00144Adenosine Deaminase Deficiency
SMP00167Adenylosuccinate Lyase Deficiency
SMP00168AICA-Ribosiduria
SMP00427Azathioprine Action Pathway
SMP00365Gout or Kelley-Seegmiller Syndrome
SMP00364Lesch-Nyhan Syndrome (LNS)
SMP00428Mercaptopurine Action Pathway
SMP00536Mitochondrial DNA depletion syndrome
SMP00203Molybdenum Cofactor Deficiency
SMP00537Myoadenylate deaminase deficiency
SMP00050Purine Metabolism
SMP00210Purine Nucleoside Phosphorylase Deficiency
SMP00430Thioguanine Action Pathway
SMP00220Xanthine Dehydrogenase Deficiency (Xanthinuria)
SMP00512Xanthinuria type I
SMP00513Xanthinuria type II
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