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MGP000153

Record overview

MGPD IDMGP000153
Gene ID292
SpeciesHomo sapiens (Human)
Gene Namesolute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
Gene Symbol SLC25A5
SynonymsT2; T3; 2F1; AAC2; ANT2;
Alternate namesADP/ATP translocase 2; ADP,ATP carrier protein 2; ADP,ATP carrier protein, fibroblast isoform; ADP/ATP carrier protein; ANT 2; adenine nucleotide translocator 2 (fibroblast); solute carrier family 25 member 5;
ChromosomeX
Map LocationXq24
SummaryThis gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]
OrthologsView orthologs and multiple alignments for SLC25A5

Proteins

ADP/ATP translocase 2
Refseq ID:NP_001143
Protein GI:156071459
UniProt ID:P05141
mRNA ID:NM_001152
Length:298
RefSeq Status:
MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFL
GGVDKRTQFWLYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKG
MLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT
 
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