MGP Database

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MGP000456

Ontology/Pathway Information

Entrez Gene ID929
Gene NameCD14 molecule
Gene Symbol CD14
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031225 IEA:UniProtKB-KWCanchored component of membrane
GO:0009986 IEA:EnsemblCcell surface
GO:0010008 TAS:ReactomeCendosome membrane
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0045121 IEA:EnsemblCmembrane raft
GO:0005886 TAS:ReactomeCplasma membrane
GO:0001530 IDA:MGIFlipopolysaccharide binding
GO:0070891 IDA:MGIFlipoteichoic acid binding
GO:0001847 TAS:BHF-UCLFopsonin receptor activity
GO:0016019 TAS:ProtIncFpeptidoglycan receptor activity
GO:0006915 TAS:ProtIncPapoptotic process
GO:0007166 TAS:ProtIncPcell surface receptor signaling pathway
GO:0071222 IDA:MGIPcellular response to lipopolysaccharide
GO:0071223 IDA:MGIPcellular response to lipoteichoic acid
GO:0007249 TAS:ReactomePI-kappaB kinase/NF-kappaB signaling
GO:0006954 IEA:UniProtKB-KWPinflammatory response
GO:0045087 TAS:ReactomePinnate immune response
GO:0002755 TAS:ReactomePMyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS:ReactomePMyD88-independent toll-like receptor signaling pathway
GO:0006909 TAS:ProtIncPphagocytosis
GO:0050715 IEA:EnsemblPpositive regulation of cytokine secretion
GO:0045807 IEA:EnsemblPpositive regulation of endocytosis
GO:0032760 IDA:MGIPpositive regulation of tumor necrosis factor production
GO:0051602 IEA:EnsemblPresponse to electrical stimulus
GO:0045471 IEA:EnsemblPresponse to ethanol
GO:0009408 IEA:EnsemblPresponse to heat
GO:0032026 IEA:EnsemblPresponse to magnesium ion
GO:0034612 IEA:EnsemblPresponse to tumor necrosis factor
GO:0034134 TAS:ReactomePtoll-like receptor 2 signaling pathway
GO:0034138 TAS:ReactomePtoll-like receptor 3 signaling pathway
GO:0034142 TAS:ReactomePtoll-like receptor 4 signaling pathway
GO:0002224 TAS:ReactomePtoll-like receptor signaling pathway
GO:0038123 TAS:ReactomePtoll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS:ReactomePtoll-like receptor TLR6:TLR2 signaling pathway
GO:0035666 TAS:ReactomePTRIF-dependent toll-like receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6890Activated TLR4 signalling
REACT_25148Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
REACT_25374IKK complex recruitment mediated by RIP1
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_6809MyD88-independent cascade
REACT_6788MyD88:Mal cascade initiated on plasma membrane
REACT_7980Toll Like Receptor 2 (TLR2) Cascade
REACT_6783Toll Like Receptor 3 (TLR3) Cascade
REACT_6894Toll Like Receptor 4 (TLR4) Cascade
REACT_6966Toll-Like Receptors Cascades
REACT_8005Toll Like Receptor TLR1:TLR2 Cascade
REACT_8006Toll Like Receptor TLR6:TLR2 Cascade
REACT_25351TRAF6 mediated induction of TAK1 complex
REACT_6822Transfer of LPS from LBP carrier to CD14
REACT_150361TRIF-mediated programmed cell death
REACT_25281TRIF-mediated TLR3/TLR4 signaling
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