MGP Database

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MGP000548

Ontology/Pathway Information

Entrez Gene ID1128
Gene Namecholinergic receptor, muscarinic 1
Gene Symbol CHRM1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0032279 IEA:EnsemblCasymmetric synapse
GO:0043679 IEA:EnsemblCaxon terminus
GO:0030054 IEA:UniProtKB-KWCcell junction
GO:0030425 IEA:EnsemblCdendrite
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0016020 TAS:ProtIncCmembrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0014069 IEA:EnsemblCpostsynaptic density
GO:0045211 IEA:UniProtKB-SubCellCpostsynaptic membrane
GO:0008144 IEA:EnsemblFdrug binding
GO:0016907 TAS:ProtIncFG-protein coupled acetylcholine receptor activity
GO:0004435 TAS:ProtIncFphosphatidylinositol phospholipase C activity
GO:0008283 TAS:ProtIncPcell proliferation
GO:0006464 TAS:ProtIncPcellular protein modification process
GO:0050890 IEA:InterProPcognition
GO:0007213 TAS:ProtIncPG-protein coupled acetylcholine receptor signaling pathway
GO:0007186 TAS:ProtIncPG-protein coupled receptor signaling pathway
GO:0007399 TAS:ProtIncPnervous system development
GO:0007274 IEA:EnsemblPneuromuscular synaptic transmission
GO:0007207 TAS:ProtIncPphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
GO:0008284 TAS:ProtIncPpositive regulation of cell proliferation
GO:0090316 IEA:EnsemblPpositive regulation of intracellular protein transport
GO:0043270 IGI:MGIPpositive regulation of ion transport
GO:0007205 TAS:ProtIncPprotein kinase C-activating G-protein coupled receptor signaling pathway
GO:0040012 IEA:EnsemblPregulation of locomotion
GO:0046541 IEA:InterProPsaliva secretion
GO:0007165 TAS:ProtIncPsignal transduction
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_16983Amine ligand-binding receptors
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_18283G alpha (q) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_16943Muscarinic acetylcholine receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
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