MGP Database

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MGP000597

Ontology/Pathway Information

Entrez Gene ID1230
Gene Namechemokine (C-C motif) receptor 1
Gene Symbol CCR1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009897 IDA:UniProtKBCexternal side of plasma membrane
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0019957 IPI:UniProtKBFC-C chemokine binding
GO:0016493 IDA:UniProtKBFC-C chemokine receptor activity
GO:0071791 IPI:UniProtKBFchemokine (C-C motif) ligand 5 binding
GO:0035717 IPI:UniProtKBFchemokine (C-C motif) ligand 7 binding
GO:0004950 IDA:UniProtKBFchemokine receptor activity
GO:0004435 IDA:UniProtKBFphosphatidylinositol phospholipase C activity
GO:0006816 IDA:UniProtKBPcalcium ion transport
GO:0007155 TAS:ProtIncPcell adhesion
GO:0007267 IDA:UniProtKBPcell-cell signaling
GO:0007166 TAS:ProtIncPcell surface receptor signaling pathway
GO:0006874 IDA:UniProtKBPcellular calcium ion homeostasis
GO:0070098 IDA:UniProtKBPchemokine-mediated signaling pathway
GO:0006935 NAS:UniProtKBPchemotaxis
GO:0019221 NAS:UniProtKBPcytokine-mediated signaling pathway
GO:0002407 TAS:BHF-UCLPdendritic cell chemotaxis
GO:0006887 IDA:UniProtKBPexocytosis
GO:0007187 TAS:ProtIncPG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0006955 IDA:UniProtKBPimmune response
GO:0006954 TAS:ProtIncPinflammatory response
GO:0008152 IDA:GOCPmetabolic process
GO:0030502 IMP:UniProtKBPnegative regulation of bone mineralization
GO:0010629 IMP:UniProtKBPnegative regulation of gene expression
GO:0051928 IDA:UniProtKBPpositive regulation of calcium ion transport
GO:0007204 IDA:UniProtKBPpositive regulation of cytosolic calcium ion concentration
GO:0070374 IMP:UniProtKBPpositive regulation of ERK1 and ERK2 cascade
GO:0090026 IDA:UniProtKBPpositive regulation of monocyte chemotaxis
GO:0045672 IMP:UniProtKBPpositive regulation of osteoclast differentiation
GO:0009611 TAS:ProtIncPresponse to wounding
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15344Chemokine receptors bind chemokines
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14819Peptide ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
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