MGP Database

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MGP000675

Ontology/Pathway Information

Entrez Gene ID1378
Gene Namecomplement component (3b/4b) receptor 1 (Knops blood group)
Gene Symbol CR1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:UniProtKBCcell surface
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005887 IDA:UniProtKBCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0001851 IDA:UniProtKBFcomplement component C3b binding
GO:0004877 IDA:UniProtKBFcomplement component C3b receptor activity
GO:0001855 IDA:UniProtKBFcomplement component C4b binding
GO:0001861 IDA:UniProtKBFcomplement component C4b receptor activity
GO:0006958 IEA:UniProtKB-KWPcomplement activation, classical pathway
GO:0002430 IDA:GOCPcomplement receptor mediated signaling pathway
GO:0045087 TAS:ReactomePinnate immune response
GO:0045957 IDA:UniProtKBPnegative regulation of complement activation, alternative pathway
GO:0045959 IDA:UniProtKBPnegative regulation of complement activation, classical pathway
GO:1900004 IDA:UniProtKBPnegative regulation of serine-type endopeptidase activity
GO:1900005 IDA:UniProtKBPpositive regulation of serine-type endopeptidase activity
GO:0030449 TAS:ReactomePregulation of complement activation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6932Complement cascade
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_118707Regulation of Complement cascade
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