MGP Database

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MGP000686

Ontology/Pathway Information

Entrez Gene ID1399
Gene Namev-crk avian sarcoma virus CT10 oncogene homolog-like
Gene Symbol CRKL
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0005768 TAS:ReactomeCendosome
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0005070 TAS:ProtIncFSH3/SH2 adaptor activity
GO:0004871 TAS:ProtIncFsignal transducer activity
GO:0000186 TAS:ReactomePactivation of MAPKK activity
GO:0009952 IEA:EnsemblPanterior/posterior pattern specification
GO:0001568 IEA:EnsemblPblood vessel development
GO:0007507 IEA:EnsemblPheart development
GO:0035556 TAS:ProtIncPintracellular signal transduction
GO:0007254 TAS:ProtIncPJNK cascade
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0009887 IEA:EnsemblPorgan morphogenesis
GO:0060017 IEA:EnsemblPparathyroid gland development
GO:0007265 TAS:ProtIncPRas protein signal transduction
GO:0048538 IEA:EnsemblPthymus development
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75790Cytokine Signaling in Immune system
REACT_17025Downstream signal transduction
REACT_12076Frs2-mediated activation
REACT_6900Immune System
REACT_23837Interleukin-3, 5 and GM-CSF signaling
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_12005Prolonged ERK activation events
REACT_23787Regulation of signaling by CBL
REACT_22232Signaling by Interleukins
REACT_16888Signaling by PDGF
REACT_11061Signalling by NGF
REACT_12058Signalling to ERKs
REACT_111102Signal Transduction
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