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MGP001045

Record overview

MGPD IDMGP001045
Gene ID2208
SpeciesHomo sapiens (Human)
Gene NameFc fragment of IgE, low affinity II, receptor for (CD23)
Gene Symbol FCER2
SynonymsCD23; FCE2; CD23A; IGEBF; CLEC4J; BLAST-2;
Alternate nameslow affinity immunoglobulin epsilon Fc receptor; C-type lectin domain family 4, member J; CD23 antigen; fc-epsilon-RII; immunoglobulin E-binding factor; lymphocyte IgE receptor;
Chromosome19
Map Location19p13.3
SummaryThe protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
OrthologsView orthologs and multiple alignments for FCER2

Proteins

low affinity immunoglobulin epsilon Fc receptor isoform a
Refseq ID:NP_001993
Protein GI:20149533
UniProt ID:P06734
mRNA ID:NM_002002
Length:321
RefSeq Status:
MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQ
RLKSQDLELSWNLNGLQADLSSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVS
IHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESM
GPDSRPDPDGRLPTPSAPLHS
 
mat_peptide: 150..321
product: Low affinity immunoglobulin epsilon Fc receptor soluble form
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P06734.1)
calculated_mol_wt: 19203
peptide sequence: 
MELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGE
PTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESMGPDSRPDPDGRLPTPSAPLHS

mat_peptide: 150..321
product: Low affinity immunoglobulin epsilon Fc receptor soluble form
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P06734.1)
calculated_mol_wt: 19203
peptide sequence: 
MELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGE
PTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESMGPDSRPDPDGRLPTPSAPLHS
 
low affinity immunoglobulin epsilon Fc receptor isoform a
Refseq ID:NP_001207429
Protein GI:334085203
UniProt ID:P06734
mRNA ID:NM_001220500
Length:321
RefSeq Status:
Protein sequence is identical to GI:20149533 (mRNA isoform)
 
mat_peptide: 150..321
product: Low affinity immunoglobulin epsilon Fc receptor soluble form
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P06734.1)
calculated_mol_wt: 19203
peptide sequence: 
MELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGE
PTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESMGPDSRPDPDGRLPTPSAPLHS
 
low affinity immunoglobulin epsilon Fc receptor isoform b
Refseq ID:NP_001193948
Protein GI:334085205
UniProt ID:P06734
mRNA ID:NM_001207019
Length:320
RefSeq Status:
MNPPSQEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQR
LKSQDLELSWNLNGLQADLSSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSI
HSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESMG
PDSRPDPDGRLPTPSAPLHS
 
mat_peptide: 150..321
product: Low affinity immunoglobulin epsilon Fc receptor soluble form
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P06734.1)
calculated_mol_wt: 19203
peptide sequence: 
MELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGE
PTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESMGPDSRPDPDGRLPTPSAPLHS
 
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