MGP Database

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MGP001535

Ontology/Pathway Information

Entrez Gene ID3360
Gene Name5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
Gene Symbol HTR4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005768 IEA:UniProtKB-SubCellCendosome
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0016020 IDA:MGICmembrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0004993 IDA:MGIFserotonin receptor activity
GO:0007186 TAS:ProtIncPG-protein coupled receptor signaling pathway
GO:0007187 TAS:ProtIncPG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0008284 IMP:UniProtKBPpositive regulation of cell proliferation
GO:0032098 IEA:InterProPregulation of appetite
GO:0007210 IDA:GOCPserotonin receptor signaling pathway
GO:0007268 IEA:InterProPsynaptic transmission
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_16983Amine ligand-binding receptors
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19327G alpha (s) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_17064Serotonin receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00309Excitatory Neural Signalling Through 5-HTR 4 and Serotonin
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