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MGP Database

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MGP001539

Ontology/Pathway Information

Entrez Gene ID	3364
Gene Name	HUS1 checkpoint homolog (S. pombe)
Gene Symbol	HUS1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0030896	IEA:InterPro	C	checkpoint clamp complex
GO:0005737	IEA:UniProtKB-SubCell	C	cytoplasm
GO:0005730	IEA:InterPro	C	nucleolus
GO:0005654	TAS:Reactome	C	nucleoplasm
GO:0005634	IDA:UniProtKB	C	nucleus
GO:0006974	TAS:ProtInc	P	cellular response to DNA damage stimulus
GO:0071479	IDA:UniProtKB	P	cellular response to ionizing radiation
GO:0000077	IMP:UniProtKB	P	DNA damage checkpoint
GO:0006281	TAS:ProtInc	P	DNA repair
GO:0006260	TAS:Reactome	P	DNA replication
GO:0000724	IEA:Ensembl	P	double-strand break repair via homologous recombination
GO:0009790	IEA:Ensembl	P	embryo development
GO:0007093	IEA:Ensembl	P	mitotic cell cycle checkpoint
GO:0008156	IEA:Ensembl	P	negative regulation of DNA replication
GO:0006468	IEA:Ensembl	P	protein phosphorylation
GO:0001932	IEA:Ensembl	P	regulation of protein phosphorylation
GO:0009411	IEA:Ensembl	P	response to UV

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_6769	Activation of ATR in response to replication stress
REACT_115566	Cell Cycle
REACT_1538	Cell Cycle Checkpoints
REACT_828	G2/M Checkpoints