MGP Database

MGP002180

Ontology/Pathway Information

Entrez Gene ID	5020
Gene Name	oxytocin/neurophysin I prepropeptide
Gene Symbol	OXT
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005576	TAS:Reactome	C	extracellular region
GO:0005615	IEA:Ensembl	C	extracellular space
GO:0030141	IEA:Ensembl	C	secretory granule
GO:0043195	IEA:Ensembl	C	terminal bouton
GO:0042756	IEA:Ensembl	P	drinking behavior
GO:0042755	IEA:Ensembl	P	eating behavior
GO:0007565	IEA:Ensembl	P	female pregnancy
GO:0007625	IEA:Ensembl	P	grooming behavior
GO:0007507	IEA:Ensembl	P	heart development
GO:0042538	IEA:Ensembl	P	hyperosmotic salinity response
GO:0060179	IEA:Ensembl	P	male mating behavior
GO:0002125	IEA:Ensembl	P	maternal aggressive behavior
GO:0042711	IEA:Ensembl	P	maternal behavior
GO:0007613	IEA:Ensembl	P	memory
GO:0045776	IEA:Ensembl	P	negative regulation of blood pressure
GO:0060455	IEA:Ensembl	P	negative regulation of gastric acid secretion
GO:0035811	IEA:Ensembl	P	negative regulation of urine volume
GO:0045777	IEA:Ensembl	P	positive regulation of blood pressure
GO:0007204	IEA:Ensembl	P	positive regulation of cytosolic calcium ion concentration
GO:0045925	IEA:Ensembl	P	positive regulation of female receptivity
GO:0060450	IEA:Ensembl	P	positive regulation of hindgut contraction
GO:0010701	IEA:Ensembl	P	positive regulation of norepinephrine secretion
GO:0045778	IEA:Ensembl	P	positive regulation of ossification
GO:0060406	IEA:Ensembl	P	positive regulation of penile erection
GO:0032308	IEA:Ensembl	P	positive regulation of prostaglandin secretion
GO:0035815	IEA:Ensembl	P	positive regulation of renal sodium excretion
GO:0051965	IEA:Ensembl	P	positive regulation of synapse assembly
GO:0050806	IEA:Ensembl	P	positive regulation of synaptic transmission
GO:0070474	IEA:Ensembl	P	positive regulation of uterine smooth muscle contraction
GO:0002027	IEA:Ensembl	P	regulation of heart rate
GO:0051930	IEA:Ensembl	P	regulation of sensory perception of pain
GO:0014823	IEA:Ensembl	P	response to activity
GO:0001975	IEA:Ensembl	P	response to amphetamine
GO:0051591	IEA:Ensembl	P	response to cAMP
GO:0042220	IEA:Ensembl	P	response to cocaine
GO:0051602	IEA:Ensembl	P	response to electrical stimulus
GO:0032355	IEA:Ensembl	P	response to estradiol
GO:0045472	IEA:Ensembl	P	response to ether
GO:0032094	IEA:Ensembl	P	response to food
GO:0051384	IEA:Ensembl	P	response to glucocorticoid
GO:0043434	IEA:Ensembl	P	response to peptide hormone
GO:0032570	IEA:Ensembl	P	response to progesterone
GO:0034695	IEA:Ensembl	P	response to prostaglandin E
GO:0032526	IEA:Ensembl	P	response to retinoic acid
GO:0009744	IEA:Ensembl	P	response to sucrose
GO:0007165	TAS:ProtInc	P	signal transduction
GO:0030431	IEA:Ensembl	P	sleep
GO:0035176	IEA:Ensembl	P	social behavior
GO:0042713	IEA:Ensembl	P	sperm ejaculation

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_14828	Class A/1 (Rhodopsin-like receptors)
REACT_267874	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125	Disease
REACT_18283	G alpha (q) signalling events
REACT_120966	Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184	GPCR downstream signaling
REACT_21340	GPCR ligand binding
REACT_267615	Metabolic disorders of biological oxidation enzymes
REACT_14819	Peptide ligand-binding receptors
REACT_14797	Signaling by GPCR
REACT_111102	Signal Transduction
REACT_17041	Vasopressin-like receptors