MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP002392

Record overview

MGPD IDMGP002392
Gene ID5515
SpeciesHomo sapiens (Human)
Gene Nameprotein phosphatase 2, catalytic subunit, alpha isozyme
Gene Symbol PPP2CA
SynonymsRP-C; PP2Ac; PP2CA; PP2Calpha;
Alternate namesserine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; protein phosphatase 2A catalytic subunit, alpha isoform; replication protein C; serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform;
Chromosome5
Map Location5q31.1
EC Number3.1.3.16
SummaryThis gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PPP2CA

Proteins

serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
Refseq ID:NP_002706
Protein GI:4506017
UniProt ID:P67775
mRNA ID:NM_002715
Length:309
RefSeq Status:
MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLL
VALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLW
SDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHV
TRRTPDYFL
 
  logo