MGP Database

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MGP002699

Ontology/Pathway Information

Entrez Gene ID6194
Gene Nameribosomal protein S6
Gene Symbol RPS6
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0044297 IDA:ParkinsonsUK-UCLCcell body
GO:0005737 IDA:HPACcytoplasm
GO:0036464 IDA:ParkinsonsUK-UCLCcytoplasmic ribonucleoprotein granule
GO:0005829 TAS:ReactomeCcytosol
GO:0022627 IDA:UniProtKBCcytosolic small ribosomal subunit
GO:0030425 IDA:ParkinsonsUK-UCLCdendrite
GO:0016020 IDA:UniProtKBCmembrane
GO:0005730 IDA:UniProtKBCnucleolus
GO:0005634 IDA:UniProtKBCnucleus
GO:0048471 IEA:EnsemblCperinuclear region of cytoplasm
GO:0005844 IEA:EnsemblCpolysome
GO:0030529 IDA:MGICribonucleoprotein complex
GO:0015935 IDA:UniProtKBCsmall ribosomal subunit
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0019901 IPI:UniProtKBFprotein kinase binding
GO:0003735 IEA:InterProFstructural constituent of ribosome
GO:0006924 IEA:EnsemblPactivation-induced cell death of T cells
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0048821 IEA:EnsemblPerythrocyte development
GO:0000082 IEA:EnsemblPG1/S transition of mitotic cell cycle
GO:0007369 IEA:EnsemblPgastrulation
GO:0010467 TAS:ReactomePgene expression
GO:0042593 ISS:UniProtKBPglucose homeostasis
GO:0008286 TAS:ReactomePinsulin receptor signaling pathway
GO:0007093 IEA:EnsemblPmitotic cell cycle checkpoint
GO:0007067 IEA:EnsemblPmitotic nuclear division
GO:0016071 TAS:ReactomePmRNA metabolic process
GO:0043066 IEA:EnsemblPnegative regulation of apoptotic process
GO:0000184 TAS:ReactomePnuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0022605 IEA:EnsemblPoogenesis stage
GO:0001890 IEA:EnsemblPplacenta development
GO:0043065 IDA:UniProtKBPpositive regulation of apoptotic process
GO:0000028 IEA:EnsemblPribosomal small subunit assembly
GO:0042274 IMP:UniProtKBPribosomal small subunit biogenesis
GO:0016070 TAS:ReactomePRNA metabolic process
GO:0006364 IMP:UniProtKBPrRNA processing
GO:0006614 TAS:ReactomePSRP-dependent cotranslational protein targeting to membrane
GO:0033077 IEA:EnsemblPT cell differentiation in thymus
GO:0002309 IEA:EnsemblPT cell proliferation involved in immune response
GO:0031929 IDA:UniProtKBPTOR signaling
GO:0006412 IC:UniProtKBPtranslation
GO:0006414 TAS:ReactomePtranslational elongation
GO:0006413 TAS:ReactomePtranslational initiation
GO:0006415 TAS:ReactomePtranslational termination
GO:0019058 TAS:ReactomePviral life cycle
GO:0016032 TAS:ReactomePviral process
GO:0019083 TAS:ReactomePviral transcription
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1258Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
REACT_2099Cap-dependent Translation Initiation
REACT_116125Disease
REACT_1477Eukaryotic Translation Elongation
REACT_2159Eukaryotic Translation Initiation
REACT_1986Eukaryotic Translation Termination
REACT_1797Formation of a pool of free 40S subunits
REACT_1079Formation of the ternary complex, and subsequently, the 43S complex
REACT_71Gene Expression
REACT_2085GTP hydrolysis and joining of the 60S ribosomal subunit
REACT_150210IGF1R signaling cascade
REACT_6167Influenza Infection
REACT_6145Influenza Life Cycle
REACT_6152Influenza Viral RNA Transcription and Replication
REACT_1195Insulin receptor signalling cascade
REACT_332IRS-mediated signalling
REACT_762IRS-related events
REACT_150203IRS-related events triggered by IGF1R
REACT_79L13a-mediated translational silencing of Ceruloplasmin expression
REACT_17015Metabolism of proteins
REACT_6964mTORC1-mediated signalling
REACT_6838mTOR signalling
REACT_75886Nonsense-Mediated Decay (NMD)
REACT_75822Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
REACT_75768Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
REACT_1404Peptide chain elongation
REACT_976PI3K Cascade
REACT_456PKB-mediated events
REACT_931Ribosomal scanning and start codon recognition
REACT_6754S6K1-mediated signalling
REACT_6772S6K1 signalling
REACT_498Signaling by Insulin receptor
REACT_150359Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
REACT_111102Signal Transduction
REACT_115902SRP-dependent cotranslational protein targeting to membrane
REACT_1014Translation
REACT_1979Translation initiation complex formation
REACT_9491Viral mRNA Translation
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