MGP Database

MGP002779

Record overview

MGPD ID	MGP002779
Gene ID	6354
Species	Homo sapiens (Human)
Gene Name	chemokine (C-C motif) ligand 7
Gene Symbol	CCL7
Synonyms	FIC; MARC; MCP3; NC28; MCP-3; SCYA6; SCYA7;
Alternate names	C-C motif chemokine 7; monocyte chemoattractant protein 3; monocyte chemotactic protein 3; small inducible cytokine A7 (monocyte chemotactic protein 3); small-inducible cytokine A7;
Chromosome	17
Map Location	17q11.2-q12
Summary	This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008]
Orthologs	View orthologs and multiple alignments for CCL7

Proteins

C-C motif chemokine 7 precursor

Refseq ID:	NP_006264
Protein GI:	13435402
UniProt ID:	P80098
mRNA ID:	NM_006273
Length:	99
RefSeq Status:

`MKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL`

sig_peptide: 1..23
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P80098.3)
calculated_mol_wt: 2262
peptide sequence: 
MKASAALLCLLLTAAAFSPQGLA

mat_peptide: 24..99
product: C-C motif chemokine 7
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P80098.3)
calculated_mol_wt: 8956
peptide sequence: 
QPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL